Wound healing is a complex biochemical process. The use of herbal medicine in wound healing not only carries forward the wisdom of traditional medicine, with its anti-inflammatory and immune-regulating effects, but also reflects the direction of modern biopharmaceutical technology, such as its potential in developing new biomaterials like hydrogels. This article first outlines the inherent structural properties of healthy skin, along with the physiological characteristics related to chronic wounds in patients with diabetes and burns. Subsequently, the article delves into the latest advancements in clinical and experimental research on the impact of active constituents in herbal medicine on wound tissue regeneration, summarizing existing studies on the mechanisms of various herbal medicines in the healing of diabetic and burn wounds. Finally, the paper thoroughly examines the application and mechanisms of plant polysaccharide hydrogels containing active herbal compounds in chronic wound healing. The primary objective is to provide valuable resources for the clinical application and development of herbal medicine, thereby maximizing its therapeutic potential. It also represents the continuation of traditional medical wisdom, offering new possibilities for advancements in regenerative medicine and wound care.
关键词:
有效成分;中草药;水凝胶;草药多糖;伤口愈合
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This work was supported by the Science Foundation Project of Heilongjiang Province of China (No. LH2021H098); National Natural Science Foundation of China (No. 82074025); the Heilongjiang Touyan Innovation Team Program, Self-funded Project of Science and Technology Plan of Harbin Science and Technology Bureau (No. 2022ZCZJNS049) and Heilongjiang Postdoctoral Fund (No. LBH-Z23276).
Ru Yan a, b, Yanhong Wang a, b, Weinan Li a, b,*, Jialin Sun c, d,*. Promotion of chronic wound healing by plant-derived active ingredients and research progress and potential of plant polysaccharide hydrogels[J]. Chinese Herbal Medicines (CHM),2025,17(1):70-83
