In Northeast China, Goubao pickle is a popular food fermented from the roots of Platycodon grandiflorum as the main material, offering a unique flavor and rich nutritional value. Platycosides in roots of P. grandiflorum may play a crucial role in determining the quality of Goubao pickle through microorganism fermentation. However, biotransfermation of platycosides has not been reviewed during fermentation. In this study, we reviewed platycosides in chemical diversity, metabolic processes in vivo, biotransformation of platycosides in vitro, and pharmacological effects. Finally, we also discussed how to improve the bioactive secondary platycosides we desire by regulating enzymes from microorganisms in the future.
关键词:
生物转化, 狗宝咸菜, 微生物, 药理作用, 桔梗皂苷, 桔梗
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This work was financially supported by the National Natural Science Foundation of China (No. U20A20400) and the Scientific Research Foundation of Heilongjiang Provincial Scientific Research Institutes (No. CZKYF2021A002). Young and middle-aged graduate tutor training program of Shenyang Agricultural University (No. 2022-ZZDS-09).
Lin Shi a, Tong Cui a, Xinyue Wang a, Rina Wu a,*, Junrui Wua, Yanqun Wang a, Weiming Wang b,*. Biotransformation and pharmacological activities of platycosides from Platycodon grandiflorum roots[J]. Chinese Herbal Medicines (CHM),2024,16(3):392-400
