Platycodonis Radix (Jiegeng in Chinese) is a well-known traditional Chinese medicine used for both medicinal and culinary purposes. Its historical use as an antitussive and expectorant has been extensively documented. Researchers, to date, have identified 219 chemical constituents in Platycodon grandiflorum (Jacq.) A. DC, encompassing 89 saponins, 11 flavonoids, 21 polysaccharides, 14 phenolic acids, six polyacetylenes, five sterols, 34 fatty acids, 17 amino acids, and 22 trace elements. Jiegeng exhibits diverse pharmacological effects, including antitussive and anti-phlegm properties, anti-cancer activity, antiinflammatory effects, immune regulation, antioxidant properties, anti-obesity, and antidiabetic effects. Additionally, Jiegeng shows potential in protecting the heart and liver. Beyond its medicinal benefits, Jiegeng is highly esteemed in culinary applications, and its global demand is on the rise. Its utilization has expanded beyond medicine and food to encompass daily necessities, cosmetics, agricultural supplies, and other fields. Currently, there are 18 272 patents related to P. grandiflorum. This comprehensive review summarizes the latest research published over the past 20 years, providing a robust foundation for further exploration of the medicinal and health benefits of P. grandiflorum.
The work was supported by the National Key Research and Development Program of China (No. 2022YFC3501805) for financial support. And we would like to thank Editage (www.editage.cn) for English language editing.
Lanying Zhang a, c, Xinrui Wanga, c, Jingze Zhang c, Dailin Liu a, c,*, Gang Bai b,*. Ethnopharmacology, phytochemistry, pharmacology and product application of Platycodon grandiflorum: A review[J]. Chinese Herbal Medicines (CHM),2024,16(3):327-343
Lanying Zhang a, c, Xinrui Wanga, c, Jingze Zhang c, Dailin Liu a, c,*, Gang Bai b,*. Ethnopharmacology, phytochemistry, pharmacology and product application of Platycodon grandiflorum: A review[J]. Chinese Herbal Medicines (CHM),2024,16(3):327-343
Lanying Zhang a, c, Xinrui Wanga, c, Jingze Zhang c, Dailin Liu a, c,*, Gang Bai b,*. Ethnopharmacology, phytochemistry, pharmacology and product application of Platycodon grandiflorum: A review[J]. Chinese Herbal Medicines (CHM),2024,16(3):327-343
Lanying Zhang a, c, Xinrui Wanga, c, Jingze Zhang c, Dailin Liu a, c,*, Gang Bai b,*. Ethnopharmacology, phytochemistry, pharmacology and product application of Platycodon grandiflorum: A review[J]. Chinese Herbal Medicines (CHM),2024,16(3):327-343
Lanying Zhang a, c, Xinrui Wanga, c, Jingze Zhang c, Dailin Liu a, c,*, Gang Bai b,*. Ethnopharmacology, phytochemistry, pharmacology and product application of Platycodon grandiflorum: A review[J]. Chinese Herbal Medicines (CHM),2024,16(3):327-343
[17]XIANG Zhi,LI Huanjie,SHEN Xinyang,LIN Haokai,PENG Caiyun,WANG Wei,YU Huanghe.药食同源植物杜仲化学成分、药理作用及产品开发的研究概况[J].China Journal of Experimental Traditional Medical Formulae,2024,30(2):190-202.
Lanying Zhang a, c, Xinrui Wanga, c, Jingze Zhang c, Dailin Liu a, c,*, Gang Bai b,*. Ethnopharmacology, phytochemistry, pharmacology and product application of Platycodon grandiflorum: A review[J]. Chinese Herbal Medicines (CHM),2024,16(3):327-343
Lanying Zhang a, c, Xinrui Wanga, c, Jingze Zhang c, Dailin Liu a, c,*, Gang Bai b,*. Ethnopharmacology, phytochemistry, pharmacology and product application of Platycodon grandiflorum: A review[J]. Chinese Herbal Medicines (CHM),2024,16(3):327-343
Lanying Zhang a, c, Xinrui Wanga, c, Jingze Zhang c, Dailin Liu a, c,*, Gang Bai b,*. Ethnopharmacology, phytochemistry, pharmacology and product application of Platycodon grandiflorum: A review[J]. Chinese Herbal Medicines (CHM),2024,16(3):327-343
Lanying Zhang a, c, Xinrui Wanga, c, Jingze Zhang c, Dailin Liu a, c,*, Gang Bai b,*. Ethnopharmacology, phytochemistry, pharmacology and product application of Platycodon grandiflorum: A review[J]. Chinese Herbal Medicines (CHM),2024,16(3):327-343
