The seco-prezizaane-type sesquiterpenes (SPS), as a special class of sesquiterpenes with a highly oxidative five-ring cage structure and seven consecutive chiral centers, are isolated from the genus Illicium, which have a variety of biological activities, including neurotoxicity and neurotrophic effects, etc. This review summarizes the chemical constituents and pharmacological effects of SPS, and discusses the potential trend and scope of future research.
关键词:
莽草毒素;化学成分;八角属;大八角素;药理作用;裂环prezizaane型倍半萜
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This work was financially supported by Yunnan Provincial Science and Technology Department-Applied Basic Research Joint Special Funds of Chinese Medicine (No. 202101AZ070001-004); Major Science and Technology Special Project from Yunnan Provincial Science and Technology Department (No. 202202AA100009, 202302AA310006); Universities Engineering Research Center of Yunnan Province (No. 2020YGG01), and Open and Shared Public Science and Technology Service Platform of Traditional Chinese Medicine Science and Technology Resources in Yunnan.
Ye Jin a, Yanqing Xie a, Peng Zhang a, Afsar Khan b, Zhihong Zhou a, Lu Liu a,*. Chemical composition and pharmacological activity of seco-prezizaane-type sesquiterpenes[J]. Chinese Herbal Medicines (CHM),2024,16(1):70-81
