Archive > Volume 16 Issue 1 > 2024,16(1):3-12. DOI:https://doi.org/10.1016/j.chmed.2023.11.002 Prev Next

中草药囊泡研究与应用专家共识（2023年版）

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Consensus statement on research and application of Chinese herbal medicine derived extracellular vesicles-like particles (2023 edition)

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    摘要:
    为推动中草药囊泡的发展特别是标准的建立，在中国研究型医院学会细胞外囊泡研究与应用专业委员会和中草药囊泡广东省工程研究中心的支持下，由全国中草药囊泡研究与应用专家委员会牵头，邀请全国中草药囊泡领域的研究专家，在整理相关文献的基础上，以德尔菲法、共识会议与名义小组相结合的方法，形成“中草药囊泡研究与应用专家共识（2023年版）”讨论稿。以线上线下会议方式，共同就中草药细胞外囊泡的研究现状、命名方法、分离方法、质量标准和研究应用等问题进行多轮磋商，最终达成13条一致意见。本共识突出中医药特色和优势，传承精华、守正创新，为国内外从事中草药囊泡研究应用提供参考，共同解码中草药囊泡背后的奥秘，为未来建立安全、有效、可控的精准化中草药囊泡防治体系，架起中医药走向世界的桥梁。

    Abstract:
    To promote the development of extracellular vesicles of herbal medicine especially the establishment of standardization, led by the National Expert Committee on Research and Application of Chinese Herbal Vesicles, research experts in the field of herbal medicine and extracellular vesicles were invited nationwide with the support of the Expert Committee on Research and Application of Chinese Herbal Vesicles, Professional Committee on Extracellular Vesicle Research and Application, Chinese Society of Research Hospitals and the Guangdong Engineering Research Center of Chinese Herbal Vesicles. Based on the collation of relevant literature, we have adopted the Delphi method, the consensus meeting method combined with the nominal group method to form a discussion draft of "Consensus statement on research and application of Chinese herbal medicine derived extracellular vesicles-like particles (2023)". The first draft was discussed in online and offline meetings on October 12, 14, November 2, 2022 and April and May 2023 on the current status of research, nomenclature, isolation methods, quality standards and research applications of extracellular vesicles of Chinese herbal medicines, and 13 consensus opinions were finally formed. At the Third Academic Conference on Research and Application of Chinese Herbal Vesicles, held on May 26, 2023, Kewei Zhao, convenor of the consensus, presented and read the consensus to the experts of the Expert Committee on Research and Application of Chinese Herbal Vesicles. The consensus highlights the characteristics and advantages of Chinese medicine, inherits the essence, and keeps the righteousness and innovation, aiming to provide a reference for colleagues engaged in research and application of Chinese herbal vesicles at home and abroad, decode the mystery behind Chinese herbal vesicles together, establish a safe, effective and controllable accurate Chinese herbal vesicle prevention and treatment system, and build a bridge for Chinese medicine to the world.

    关键词:
    中草药;囊泡;研究应用;质量标准;专家共识

    Keywords:


    Project Supported:
    It is a collaborative effort between the Expert Committee on Research and Application of Chinese Herbal Vesicles, Professional Committee on Extracellular Vesicle Research and Application, Chinese Society of Research Hospitals and Guangdong Provincial Association of Chinese Medicine, and the Guangdong Engineering Research Center of Chinese Herbal Vesicles, who have jointly proposed and published this consensus. This work was supported by the National Science Foundation of China (No. 82174119), Young Talent Support Project of Guangzhou Association for Science and Technology (No. QT2023036), Science and Technology Projects in Liwan District, Guangzhou (No. 20230710 and 202201009), and Special Focus Areas for General Universities in Guangdong Province (No. 2022ZDZX2016).

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