Chemical Constituents from Leaves of Oplopanax horridus
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Abstract:
Objective To study the chemical constituents from the leaves of Oplopanax horridus. Methods The chemical constituents were isolated and purified by column chromatography on silica gel and Sephadex LH-20 gel columns, 1H-NMR and 13C-NMR were applied for the identification of chemical structure. Results Ten compounds were isolated and identified as dammara-20,24-dien-3β-ol acetate (1), phytol (2), 16Z,19Z- pentacosadienoic acid (3), β-sitosterol (4), (3S,8S)-falcarindiol (5), maltol (6), acankoreagenin (7), daucosterol (8), stigmasterol-3-O-β-D-glucopyranoside (9), and acankoreoside A (10). Conclusion Compounds 1-3, 6, and 10 are isolated from this plant for the first time. Compounds 1-3 and 6 are isolated from the plants in genus Oplopanax Miq. for the first time. Moreover, Compounds 1, 3, and 6 are isolated from the plants in the family of Araliaceae for the first time.
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Project Supported:
NIH/NCCAM (AT004418 and AT005362 to C. S. Yuan); University of Macau (UL015/09-Y1 to S. P. Li) grants
