A New Alkaloid from Bombycis Feculae and Its α-Glucosidase Inhibitory Activity
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A New Alkaloid from Bombycis Feculae and Its α-Glucosidase Inhibitory Activity
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Abstract:
Objective To study the chemical constituents of Bombycis Feculae. Methods Chemical constituents were isolated by HPLC-ELSD. The structures of the isolated compounds were determined by spectral means. Results Two compounds were isolated and identified as 1-deoxynojirimycin (1) and (2R,3R,5R)-2-(hydroxymethyl) piperidine-3,5-diol, named as 1,3-dideoxygalatonojirimycin (2). Conclusion Compound 2 is a new alkaloid. The extract of Bombycis Feculae, compound 1 and compound 2 show inhibitory activities against α-glucosidase.
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Key National Science & Technology Specific Projects (2009ZX09103-363)
ZHU Yuan-yuan, WANG Zhi-hong, QI Hui, BAI Gang. A New Alkaloid from Bombycis Feculae and Its α-Glucosidase Inhibitory Activity[J]. Chinese Herbal Medicines (CHM),2011,3(1):64-65