[关键词]
[摘要]
海马Hippocampus为我国名贵珍稀动物类药材,其化学成分种类丰富,含有氨基酸、活性多肽、甾体类、脂肪酸和微量元素等多种化学成分。海马为传统补益类药材,药理作用广泛,其主要的药理活性包括性激素样作用、抗炎、抗氧化、抗肿瘤和提高机体免疫力等。通过查阅近年来国内外的相关文献,就海马的化学成分和药理作用等方面研究进展进行系统综述,结合课题组前期的工作对海马药材的相关问题进行了讨论与展望,以期为海马的临床应用和后续产品开发提供依据和参考。
[Key word]
[Abstract]
Hippocampus has been widely used as a precious animal medicinal materials with long history in China. The major chemical constituents of Hippocampus contain amino acids, active polypeptides, steroids, fatty acids, and microelements, with extensive pharmacological properties, its pharmacological research mainly focused on the gonadotropic, anti-inflammatory, anti-oxidative, antineoplastic, and improving organic immunity activities. This paper reviews the advances on the chemical compositions and pharmacological activities of Hippocampus, and gives a brief discussion on the problems of Hippocampus in combination with previous results, which provides theoretical basis and references for its clinical applications and further developments.
[中图分类号]
[基金项目]
公益性行业科研专项经费项目(201507002)