[关键词]
[摘要]
目的研究超微粉碎前后川芎的粉体学性质,为超微粉碎对含挥发油类药材的影响提供依据。方法采用激光粒度分析仪测定粉末粒径及粒度分布;生物显微镜进行显微学研究;测定粉体休止角和堆密度,测定25℃相对湿度为75%条件下粉体的吸湿性。结果 川芎超微粉和普通粉的D50分别为14.58、58.54μm,且超微粉粒度分布均匀性较好;显微镜下可见超微粉和普通粉在显微特征上都有较大的区别,油滴显著减小;超微粉碎对川芎粉体的流动性、堆密度和吸湿性没有显著的影响。结论 超微粉碎后细胞破壁率显著增大,均匀度得到改善,其中油滴的显著减小为挥发油类药材超微粉碎形成"乳化结构"的证实提供了初步的依据和借鉴。流动性、堆密度和吸湿性无显著变化,说明富含挥发油的川芎在粉体学性质上有其特殊性。
[Key word]
[Abstract]
Objective To study the micromeritics of common powder and superfine powder of Chuan-xiong Rhizoma.Methods Particle size and particle size distribution were detected by laser particle analyzer;Microscopic characteristics of the two sorts of powder of Chuanxiong Rhizoma were surveyed by biological microscope;The angle of repose and the bulk density were measured;The moisture absorption of common powder and superfine powder were determined on condition of 25 ℃ and relative humidity of 75%.Results D50 of common powder and superfine powder were 14.58 and 58.54 μm,and the superfine powder was more uniformly distributed.There were many differences between superfine powder and common powder in microscopic characteristics,including greatly smaller oil droplets in superfine powder.There was no significant change in flow ability,bulk density,and moisture absorption.Conclusion After being superfinely comminuted,the powder of Chuanxiong Rhizoma is more uniformly distributed with greatly increased broken cell wal1.The oil droplets are much smaller in surperfine powder,which provides a preliminary basis for "emulsification structure".There is no significant change in flow ability,bulk density,and moisture absorption because of rich volatile oil in Chuanxiong Rhizoma.
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[基金项目]
广东省自然科学基金资助项目(8451051501000166)