对4种川紫菀及紫菀进行了祛痰镇咳的药理作用比较，结果表明4种州紫菀均具明显的镇咳祛痰作用，与相同剂量的紫菀无明显差异。

Shanziwan, the root and rhizome of Ligularia Cass., has been used as a substitute for Ziwan (root of Aster tataricus L.f.) in traditional Chinese medicine (TCM) for centuries, and is still used either in mainland China, Hong Kong and other Chinese communities worldwide. As documented in the local pharmacopoeias of Sichuan, Guizhou and Yunnan provinces, various Ligularia sp., including L. hodgsonii, L. intermedia, L. wilsoniana and L. sibirica var.araneosa, are defined as the authentic herbal plants for “Chuanziwan” in Sichuan and Guizhou provinces, clinically utilized as a replacement for Ziwan with similar antitussive and expectorant actions to those of Ziwan. However, there are no reported scientific evidence to support such a substitution. In the present studies, a comparison of the antitussive and expectorant effects between Ligularia sp.and Aster tataricus in mice has been conducted. The result showed that the aqueous extracts of both Shanziwan and Ziwan produce antitussive and expectorant effects with a similar potency at the same dosage.

国家“八·五”攻关项目;国家自然科学基金及香港政府研究资助