Objective: To study the chemical constituents from the roots of Curcuma longa. Methods: The structures of the new compounds were elucidated based on extensive spectral analysis, including 1D and 2D NMR, MS, UV, and CD analysis. Results: Two new sesquiterpene compounds (1S,2R,5R,7S,8R)-2,8-epoxy-5-hydroxybisabola-3,10-dioen-9-one (1), (1R,2R,5R,7S,8R)-2,8-epoxy-5-hydroxybisabola-3,10-dioen-9-one (2), and a new natural product 6-(4-Hydroxymethylphenyl)-2-methyl-hept-2-ene-4-one (3) together with three known compounds ar-turmerone (4), 2-methyl-6-(4-hydroxyphenyl-3-methyl)-2-hepten-4-one (5) and 2-methyl-6-(4-hydroxyphenyl)-2-hepten-4-one (6) were isolated from C. longa root extract with 95% ethanol. Conclusion: In the study, three new compounds were isolated from C. longa, and their absolute configurations were determined.
关键词:
姜黄;化学成分;姜黄素;核磁共振;倍半萜
Keywords:
Project Supported:
Sub-project of National Basic Science Talent Training Fund (No. J1103606).
Jie Zhang a,, Xiaorui Ma b,, Wei Wang a, Caixia Wu a, Ben Ma a, Chong Yu a, Haifeng Wang a*. Three new sesquiterpenes from roots of Curcuma longa[J]. Chinese Herbal Medicines (CHM),2023,15(3):470-474
