Quinoline alkaloids isolated from Scolopendra subspinipes mutilans
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摘要:
Abstract:
Objective To study the quinoline alkaloids from the ethanol extract of Scolopendra subspinipes mutilans (SSM). Methods The chemical constituents were isolated and purified by macroporous resin column, medium pressure preparation chromatography, and semi-preparative HPLC. Their structures were elucidated by IR, MS, and NMR experiments. Results Three quinolone alkaloids were obtained and identified as 3-hydroxy-4-methoxyquinolin-8-yl hydrogen sulfate (1), jineol-8-sulfate (2), and jineol (3), respectively. Conclusion Compound 1 is a new compound from SSM.
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The author would like to thank professor Feng-qing Xu and Guokai Wang from Anhui University of Chinese Medicine for reviewing this paper. We also thank Shandong Analysis and Test Center for the measurement of the NMR spectra. This project was supported by the Special Project (nNo.1811) for the Scientific & Technological Innovation and Development of Lanshan District, Linyi.