Objective To study the chemical constituents of the fungus Ganoderma cochlear. Methods The compounds were isolated by using MCI gel CHP 20P, Sephadex LH-20, RP-18 column chromatography, and preparative TLC. The structures were identified by means of spectroscopic methods. Results Two phenolic normeroterpenoid and meroterpenoid, cochlearols C and D (1 and 2), together with six benzene derivatives, 3- methoxy-4-hydroxy-phenylethanol (3), 4-hydroxyacetophenone (4), p-hydroxycinnamic methyl ester (5), 2-methoxy-4-hydroxybenzaldehyde (6), 4-hydroxy-3-methoxy benzoic acid (7), and 2-hydroxy-5-ethoxybenzoic acid (8), were isolated from the fruiting bodies of Ganoderma cochlear. Conclusion Compounds 1 and 2 are new phenolic normeroterpenoid and meroterpenoid, respectively.
关键词:
Keywords:
Project Supported:
NSFC-Joint Foundation of Yunnan Province (U1202222), National Natural Science Foundation of China (21472199), and a project from State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany (P2013-ZZ03).
