A New Hasubanan Alkaloid from Stephania hernandifolia
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摘要:
Abstract:
Objective To study the chemical constituents of Stephania hernandifolia. Methods Various chromato- graphic techniques were used to isolate the constituents, and the structures were elucidated on the basis of HR-EI-MS, 1D-NMR and 2D-NMR spectral analyses. Results A hasubanan alkaloid, hernsubanine D (1) was isolated from the whole plants of S. hernandifolia. The compound was screened for the cytotoxic activity against two human cancer cell lines in vitro. Conclusion Compound 1 is a new compound without cytotoxicity against A549 and K562 cells.
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Science and Technology Commission of China (2012CB722601); Science and Technology Department of Guizhou Province (QKHZYZ [2011] 5085)
