大黄Rhei Radix et Rhizoma是我国大宗药材之一，具有丰富的化学成分及多种药理作用，具有泻下攻积、清热泻火、凉血解毒、逐瘀通经、利湿退黄的功效，临床应用广泛。但在市场与临床中大黄质量参差不齐，大黄的品质决定其疗效，化学成分是质量评价的重要指标，大黄化学成分受种质、不同部位、环境、栽培、产地加工因素的影响。通过对大黄品质概况、化学成分、大黄化学成分品质评价及影响因素研究现状进行综述，为大黄更科学的质量评价提供参考，推动大黄产业的可持续发展。

Dahuang (Rhei Radix et Rhizoma) is one of the bulk medicinal materials in China, characterized by rich chemical compositions and diverse pharmacological effects. It has the effects of purgative accumulation, clearing away heat and fire, cooling blood and detoxifying, removing blood stasis and channeling meridian, excreting dampness and anti-icteric, and is widely used in clinical practice. However, the quality of Rhei Radix et Rhizoma varies in markets and clinic. The quality of Rhei Radix et Rhizoma determines the quality of the curative effect. Chemical composition is an important index for quality evaluation, and the chemical compositions of Rhei Radix et Rhizoma are affected by germplasm, different parts, environment, cultivation, and processing in producing area. By summarizing current research on Rhei Radix et Rhizoma quality overview, chemical compositions, and quality evaluation of chemical compositions in Rhei Radix et Rhizoma and its influencing factors, to provide a reference for a more scientific quality evaluation of Rhei Radix et Rhizoma and promote sustainable development of Rhei Radix et Rhizoma industry.

R282

财政部和农业农村部：国家现代农业产业技术体系资助（CARS-21）；甘南州技术创新引导计划项目：唐古特大黄产地初加工技术集成及示范推广（2024JY1NNC001）；甘肃省卫生健康委员会：药食同源物质基础研究（甘财社[2023]168号）