鸡血藤Spatholobi Caulis为藤茎类中药，在我国南方地区及东南亚国家药用历史悠久。研究表明鸡血藤成分复杂，主要包括黄酮类、苯丙素类、酚酸类等成分，具有调节血液系统、抗氧化、抗肿瘤及抗病毒等活性。通过对鸡血藤化学成分和药理作用进行综述，基于化学成分特有性、药性、药效、入血成分和成分可测性对鸡血藤的质量标志物（quality marker，Q-Marker）进行预测，表明儿茶素、染料木素、芒柄花素等黄酮类成分及原儿茶酸和没食子酸等酚酸类、芦荟大黄素等蒽醌类、3-羟基豆甾-5-烯-7-酮等甾体类、白芷内酯和spasuberol C等香豆素类可作为鸡血藤的主要Q-Marker，为鸡血藤的质量评价提供科学依据。

Jixueteng (Spatholobi Caulis) is a kind of vine traditional Chinese medicine, which has a long history of medicinal use in southern China and Southeast Asian countries. Studies show that Spatholobi Caulis has complex components, mainly including flavonoids, phenylpropanoids, phenolic acids and other components, which have the activities of regulating blood system, antioxidation, antitumor and anti-virus. The chemical constituents and pharmacological effects of Spatholobi Caulis were summarized, and the quality marker (Q-Marker) of Spatholobi Caulis was predicted based on the uniqueness of chemical constituents, medicinal properties, efficacy, blood components and component measurability. The results showed that flavonoids such as catechin, genistein and formononetin, phenolic acids such as protocatechuic acid and gallic acid, anthraquinones such as aloe-emodin and steroids such as 3-hydroxystigmasterol-5-ene-7-one, coumarins such as angelicin and spasuberol C could be used as the main Q-markers of Spatholobi Caulis, which provided scientific basis for the quality evaluation of Spatholobi Caulis.

国家自然科学基金资助项目（81460595）；国家自然科学基金资助项目（81960697）