[关键词]
[摘要]
目的 研究红树植物瓶花木Scyphiphora hydrophyllacea枝叶中的化学成分。方法 综合运用正、反相硅胶柱色谱和Sephadex LH-20凝胶柱色谱以及制备型高效液相色谱等方法进行系统分离纯化，根据化合物的理化性质及其波谱学数据鉴定化合物的结构。结果 从瓶花木枝叶的90%乙醇提取物中分离得到了18个化合物，分别鉴定为坡模酮酸（1）、蔷薇酸（2）、达玛二烯醇乙酸酯（3）、古柯二醇（4）、羽扇豆醇乙酸酯（5）、30-醛基羽扇豆醇（6）、山楂酸（7）、23-羟基熊果酸（8）、β-香树脂酮（9）、刺槐素（10）、金圣草黄素（11）、棕矢车菊素（12）、熊竹山姜素（13）、异樱花素（14）、花旗松素（15）、lyoniresinol（16）、杜仲树脂酚（17）和蛇菰脂醛素（18）。其中，化合物1~9为三萜类化合物，10~15为黄酮类化合物，16~18为木脂素类化合物。结论 所有化合物均为首次从瓶花木属植物中分离得到。
[Key word]
[Abstract]
Objective To study the chemical constituents of the stems and leaves of mangrove plant, Scyphiphora hydrophyllacea. Methods The chemical constituents of S. hydrophyllacea were separated and purified by silica gel, ODS, Sephadex LH-20 gel column chromatographies and preparative HPLC. Their structures were identified by physicochemical properties, spectroscopic analysis, as well as comparisons with the data reported in literatures. Results A total of 18 compounds were isolated from the 90% ethanol extract of the stems and leaves of S. hydrophyllacea, which were identified as pomonic acid (1), euscaphic acid (2), dammaradienyl acetate (3), erythrodiol (4), lupenyl acetate (5), 30-oxo-lupeol (6), maslinic acid (7), 23-hydroxyursolic acid (8), β-amyrenone (9), acacetin (10), chrysoeriol (11), jaceosidin (12), kumatakenin (13), isosakuranetin (14), taxifolin (15), lyoniresinol (16), medioresinol (17), and balanophonin (18). Compounds 1-9 were triterpenoids, compounds 10-15 were flavonoids and compounds 16-18 were lignans. Conclusion All compounds are isolated from the genus Scyphiphora for the first time.
[中图分类号]
R284.1
[基金项目]
国家自然科学基金资助项目（21967008）；国家自然科学基金资助项目（21662011）；国家自然科学基金资助项目（31660097）；海南省重点研发计划项目（ZDYF2019049）；海口市重点研发计划项目（2017050）；教育部创新团队项目（IRT-16R19）
