总结十余年来本项目研究的主要结论,结合中医清热解毒法的理论基础,对中药板蓝根的有效组分及其重要化学成分、药理活性、分子生物学等方面的研究进展、思路及方法加以综述,进一步阐明板蓝根清热解毒的实质和作用机制,以期为探讨清热解毒中药的相关活性提供新的研究途径。

In this review, the new research development on the extracts, active constituents, pharmacological activities, and molecular biological mechanisms of Radix Isatidis were summar ized through analyzing the experimental data and consulting the papers in the lastest ten years. Reports indicated the essence and mechanisms of clearing away heat and toxic material of Radix Isatidis on the basis of tr aditional Chinese medicine theory. Although this research contains some equivocal domains, it could present the new idea and approach for some relevant Chinese materia medica on clear ing away heat and toxic material

国家自然科学基金资助项目(39800193,39870872)