远志为远志科植物远志Polygala tenuifolia或卵叶远志P. sibirica的干燥根,药用历史悠久。现代研究表明,远志具有神经保护、抗氧化、抗肿瘤、抗抑郁、改善认知功能障碍及镇静催眠等药理活性,其炮制工艺与药效关联性已成为研究热点。然而,目前尚缺乏对远志古今功效关联性及整体药理作用的系统分析。通过文献计量学方法,结合本草典籍考证、《中国药典》2025年版成方制剂分析及CiteSpace可视化技术,系统梳理了远志的传统功效与现代药理活性研究,为远志的深入研究和临床应用提供参考。

Yuanzhi (Polygalae Radix) refers to the dried root of Polygala tenuifolia or P. sibirica, which belongs to Polygalaceae family. It has a long history of medicinal use. Modern research indicates that Polygalae Radix exhibits various pharmacological activities, such as neuroprotective, antioxidant, antitumor, antidepressant, cognitive-enhancing, and sedative-hypnotic effects. The relationship between its processing methods and efficacy has become a current research focus. However, there remains a lack of systematic analysis on the correlation between its traditional and modern effects of Polygalae Radix and its overall pharmacological effects. This study employs bibliometric methods, textual research on ancient materia medica texts, analytical result of formulated preparations from the Chinese Pharmacopoeia (2025 edition), and CiteSpace visualization technology to systematically review the traditional uses and modern pharmacological activities of Polygalae Radix. These findings aim to provide a theoretical reference for further research and clinical application.

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苏州市科技计划项目（SKY2021019）；常熟市卫生健康委员会科技计划项目（CSWS202120）；天津市科技计划项目（24ZYJDSS00300）；现代中药新质生产力科技创新工程专项（24ZXZKSY00010）