目的 通过CiteSpace软件对川芎Chuanxiong Rhizoma相关研究文献进行可视化分析,系统梳理近年研究动态,挖掘研究热点及未来趋势,为川芎的深度研究与应用提供参考。方法 以“川芎”为核心关键词,系统检索中国知网、万方、维普及Web of Science(WOS)数据库。利用NoteExpress软件对检索结果进行去重与筛选。基于筛选后的文献数据集,运用Excel和CiteSpace工具,从年度发文量及国家分布、核心研究机构、高产作者群体、高频关键词及其聚类等维度,对国内外川芎研究态势进行可视化呈现与计量分析。结果 筛选后共纳入8 809篇中文文献,1 076篇英文文献;其中,年发文量呈先增后减的趋势,发文量最多的国家是中国,发文量最多的作者是王万铁、Peng Cheng(彭成),作者合作网络显示团队内部合作较多,团队间合作不足;研究机构中以南京中医药大学和Chengdu University of Traditional Chinese Medicine(成都中医药大学)的发文量最多,核心机构来自中医药类的高校与附属医院;关键词分析显示中文文献的研究热点主要为化学成分分析、数据挖掘、临床研究等方面,英文文献更偏向于药理作用、分子机制等方面。结论 川芎在中医药领域的研究热度持续。现阶段,川芎在冠心病、缺血性脑卒中、偏头痛等疾病中的临床应用价值挖掘及基于数据的规律探索构成研究热点。未来研究应积极融合多种现代技术手段,深度挖掘川芎的应用潜力,拓展其临床适应证范围,推动其向多元化应用方向发展,从而为该领域开辟新的研究路径。

Objective To systematically analyze the research landscape of Chuanxiong (Chuanxiong Rhizoma) using CiteSpace for visual bibliometric analysis, identifying research hotspots and future trends to inform its in-depth research and application. Methods Literature related to “Chuanxiong Rhizoma” was retrieved from the China National Knowledge Infrastructure (CNKI), Wanfang, VIP, and Web of Science (WOS) databases. NoteExpress software was used for deduplication and screening. Excel and CiteSpace were employed to visualize and analyze the screened dataset across dimensions including annual publication volume, country distribution, core institutions, productive authors, author collaboration networks, high-frequency keywords, and keyword clusters. Results A total of 8 809 Chinese literature and 1 076 English literature were included after screening. The annual number of published papers on Chuanxiong Rhizoma showed a fluctuating trend characterized by an initial increase followed by a decline. China contributed the highest number of publications. The authors with the largest number of published papers were Wang Wantie and Peng Cheng. The author cooperation network revealed stronger intra-team collaboration, while inter-team collaboration remained limited. Among research institutions, Nanjing University of Chinese Medicine and Chengdu University of Traditional Chinese Medicine had published the most papers. Core institutions predominantly originated from universities of Traditional Chinese Medicine and their affiliated hospitals. Keywords analysis indicated that research hotspots in Chinese literature focused primarily on chemical composition analysis, data mining, and clinical research, while English literature focused more on pharmacological effects, molecular mechanism etc. Conclusion Research interest in Chuanxiong Rhizoma within traditional Chinese medicine remains strong. Current hotspots center on exploring its clinical value in diseases like coronary heart disease, ischemic stroke, and migraine, alongside data-driven pattern discovery. Future research should integrate diverse modern technologies to systematically explore Chuanxiong Rhizoma’s potential, broaden its clinical indications, and promote its diversification, thereby opening new research avenues.

G350;R282

金华市中医药科技计划（2024QN03）