[关键词]
[摘要]
目的 运用CiteSpace软件对乳香Olibanum相关研究文献进行可视化分析,旨在系统梳理近20年来国内外乳香研究的发展脉络,揭示研究热点及未来研究趋势,为乳香的基础研究与临床应用提供理论支持。方法 分别检索中国知网、万方数据和Web of Science核心合集数据库中2005年1月1日—2025年5月26日发表的乳香相关中英文文献。利用NoteExpress软件对检索结果进行去重与筛选,最终采用CiteSpace对发文数量、作者、机构、关键词共现与突现等信息进行知识图谱可视化分析。结果 共纳入中文文献943篇,英文文献43篇。年发文量整体呈上升趋势,中文文献发文量较多的作者为刘军,英文文献中代表性作者为Ding Yi(丁一);作者合作网络显示国内作者合作密切但跨机构合作有限。主要研究机构包括北京中医药大学、南京中医药大学、广州中医药大学等。关键词共现与突现分析结果显示,中文文献研究聚焦于数据挖掘、用药规律等;英文文献研究则多集中于抗炎作用、活性成分(如乳香酸)、网络药理学及作用机制等方面。结论 乳香在中医药防治骨关节病、乳腺病变、糖尿病足等疾病方面的研究热度持续上升,现代研究手段如网络药理学、分子机制解析和数据挖掘技术的广泛应用为乳香的科学研究提供了新的突破口。未来应加强多学科协作,深入挖掘乳香活性成分与靶向机制,以推动乳香在中药现代化与临床转化中的深入发展。
[Key word]
[Abstract]
Objective This study aims to employ CiteSpace software to perform a visualized bibliometric analysis of research literature related to Ruxiang (Olibanum), in order to systematically trace the development trends of domestic and international studies over the past two decades. It further seeks to identify current research hotspots and future directions, thereby providing theoretical support for both the basic and clinical application of Boswellia. Methods Relevant Chinese and English literature published between January 1, 2005 to May 26, 2025 was retrieved from China national knowledge infrastructure (CNKI), Wanfang Data, and Web of Science. After deduplication and screening using NoteExpress software, CiteSpace was employed to visually analyze the data in terms of annual publication volume, authors, institutions, keyword co-occurrence, and keyword bursts. Results A total of 943 Chinese articles and 43 English articles were included. The annual number of publications shows an overall upward trend. Among the Chinese literature, Liu Jun was identified as the most prolific author, while Ding Yi emerged as a representative author in the English literature. Author collaboration networks indicate close domestic cooperation but limited inter-institutional collaboration. The main research institutions include Beijing University of Chinese Medicine, Nanjing University of Chinese Medicine, and Guangzhou University of Chinese Medicine. Keyword co-occurrence and burst analyses revealed that Chinese studies primarily focused on data mining and medication patterns, whereas English studies emphasized anti-inflammatory effects, active constituents such as boswellic acids, network pharmacology, and mechanisms of action. Conclusion Research on Olibanum has shown sustained growth, particularly in the prevention and treatment of diseases such as osteoarthropathy, breast disorders, and diabetic foot using traditional Chinese medicine (TCM). The integration of modern techniques, such as network pharmacology, molecular mechanism analysis, and data mining has opened up new avenues for scientific inquiry. Future research should promote interdisciplinary collaboration and further exploration of active components and target mechanisms to advance the modernization and clinical translation of Boswellia in TCM.
[中图分类号]
R285
[基金项目]
国家自然科学基金面上项目(82374460);湖南省自然科学基金面上项目(2023JJ30478);国家中医优势专科-外科 [国中医药医政函 (2024) 90号];湖南省一类中医重点专科中医男科 [湘中医药函 (2023) 4号];湖南省教育厅科学研究项目(22A0282);湖南中医药大学研究生创新课题(2024CX015)