小建中汤为《伤寒杂病论》中经典名方，具有温中补虚、和里缓急的功效，是治疗脾胃虚寒、腹痛、虚劳等证的经典方剂。该方组方精巧、配伍得当，常被古今医家加减化裁用于各类内外科杂病的治疗，疗效显著。近年来，随着现代药理学的快速发展，关于小建中汤微观作用机制的研究不断发展与深化，为小建中汤治疗疾病提供了新的思路。因此，通过对小建中汤的现代临床应用进行梳理、总结，阐述了小建中汤在消化系统、呼吸系统、神经系统、内分泌系统、循环系统及其在妇科、儿科等的应用，为其后续深入的实验研究、二次开发和临床推广应用提供参考依据。

Xiaojianzhong Decoction (小建中汤) is a classic traditional Chinese medicine prescription derived from Treatise on Cold Damage and Miscellaneous Diseases, exerting the efficacy of warming the center, tonifying deficiency, harmonizing the interior, and alleviating urgency. It is a classic prescription for treating disorders such as deficiency of the spleen and stomach, abdominal pain, and deficiency syndromes. This prescription is ingeniously formulated and well-matched in its ingredients, and has been frequently modified and adapted by both ancient and modern physicians for treatment of various internal and external diseases. The therapeutic effect is remarkable. In recent years, with the rapid development of modern pharmacology, studies on the microscopic mechanism of action of Xiaojianzhong Decoction have been continuously developing and deepening, providing new ideas for the treatment of diseases with Xiaojianzhong Decoction. Therefore, by sorting out and summarizing the literature on the modern clinical application of Xiaojianzhong Decoction, this paper expounds its application in digestive system, respiratory system, nervous system, endocrine system, circulatory system, as well as in gynecology, pediatrics, etc., providing a reference basis for its subsequent in-depth experimental research, secondary development and clinical promotion and application.

R285

国家自然科学基金资助项目（82360903）；贵州省千层次创新人才项目；贵州省科学技术研究专项课题（黔科合基础-ZK [2024] 一般396）；贵州省中医药管理局中医药、民族医药科学技术研究课题（QZYY-2024-173）