历代医家对当归Angelicae Sinensis Radix药性的描述为甘、辛、苦、温；入肝、心、脾经，能升能降。随着中医药的发展和医药学家的不断实践，形成了多种各具特色与优势的当归炮制饮片，研究表明不同的炮制技术会改变其药性，从而在临床应用上有特定的优势。通过系统梳理当归各炮制品的分类、历代炮制方法及现代使用情况，并基于中药药性理论从物质基础、药理学和代谢组学层面阐明不同炮制品的药性变化和临床应用甄别，为当归炮制方法的传承、临床实践提供理论依据，同时为未来研究方向提出建议，推动其在中药炮制中更广泛的应用。

The medicinal properties of Danggui (Angelicae Sinensis Radix) were described as sweet, pungent, bitter and warm. It enters the liver, heart and spleen meridians and can ascend and descend. With the development of traditional Chinese medicine and the continuous practice of medical scholars, a variety of processed Angelicae Sinensis Radix decoction pieces with distinct characteristics and advantages have been formed. Studies have shown that different processing techniques can alter its medicinal properties, thereby endowing it with specific advantages in clinical application. In this paper, the classification, processing methods and modern use of Angelicae Sinensis Radix products were systematically reviewed. Based on the theory of traditional Chinese medicine properties, the changes of medicinal properties of different Angelicae Sinensis Radix products and the screening of clinical applications were expounded from the aspects of material basis, pharmacology and metabolomics, aiming to provide theoretical basis for the inheritance of Angelicae Sinensis Radix processing methods and clinical practice, and at the same time, suggestions for future research directions were put forward. Promoting its wider application in processing of traditional Chinese medicine.

R28

国家重点研发计划“中医药现代化研究”重点专项（2023YFC3504205）；特色炮制技术规律发掘——麸制（GZY-KJS-2022-051）；中药炮制技术传承创新团队（CXTD22003）；中药炮制（炆法）等关键技术重点研究室（赣中医药科教字 [2022] 8号）；江西省“双千人才”计划项目 [赣才办字（2019）9号]；江西省中医药产业科技创新联合体产业链协同攻关项目（20224BBG72001）；江西省自然科学基金项目（20224ACB206048）；国家自然科学基金资助项目（82360771）；中药炮制传承创新与转化江西省重点实验室（2024SSY07091）；江西省标准创新基地（医药）​；国家重点研发计划“中医药现代化研究”重点专项（2024YFC3507005）；江西​中医药大学研究生创新专项（XJ-S202481）