目的 对2011—2025年新兴热门领域AI＋中药活性多糖的发展趋势和研究热点进行知识图谱分析，为该领域的进一步发展提供实用性参考。方法 全面检索Web of Science（WOS）中的相关英文文献，使用VOSviewer和CiteSpace 2种重要文献计量学工具进行可视化分析，包括发文趋势、国家和期刊分布、作者与机构合作网络分析，关键词共现、聚类、时间线和突现分析以及高被引文献分析。结果 最终得到AI＋中药活性多糖研究领域高质量文献116篇，发文趋势呈现新兴学科演进特征，中国和美国是发文量最多的国家，International Journal of Biological Macromolecules是发表论文最多的期刊，中国科学院为核心机构。研究热点涵盖智能算法驱动的中药活性多糖提取、分离、鉴定及活性预测，多糖基生物材料的智能化开发，以及精准医疗与癌症疾病预防调控等方向。结论 AI＋中药活性多糖当前研究热点具有极大研究前景，研究领域展现高速发展态势，有可能成为未来重要的研究方向。

Objective To analyze the knowledge mapping of the development trend and research hotspots in the emerging hot field of AI + active polysaccharides in traditional Chinese medicine from 2011 to 2025, so as to provide a practical reference for the further development of this field. Methods A comprehensive search of relevant English literature in Web of Science (WOS) was conducted, and 2 important bibliometric tools, VOSviewer and CiteSpace, were used to perform visual analysis, including the trend of publications, distribution of countries and journals, network analysis of authors’ and institutions’ cooperation, keyword co-occurrence, clustering, timeline and emergence analyses as well as the analysis of highly cited literature. Results Finally, a total of 116 high-quality literatures were obtained in the research field of AI + active polysaccharides in traditional Chinese medicine, and the trend of publication showed the characteristics of emerging disciplinary evolution, with China and the United States being the countries with the largest number of publications, International Journal of Biological Macromolecules being the journal with the largest number of publications, and Chinese Academy of Sciences being the core institution. The research hotspots cover intelligent algorithm-driven polysaccharide extraction, isolation, characterization and activity prediction, intelligent development of polysaccharide-based biomaterials, and precision medicine and cancer prevention and regulation. Conclusion The current research hotspots of AI + active polysaccharides in traditional Chinese medicine have great research prospects, and the research field shows a rapid development trend, which may become an important research direction in the future.

G350;R285

国家自然科学基金资助项目（U2202213）；国家自然科学基金资助项目（82374098）