[关键词]
[摘要]
目的 运用文献计量学方法剖析龙眼肉Longan Arillus的研究现状,预测其未来研究热点及发展趋势。方法 以中国知网(CNKI)、万方数据知识服务平台(WF)、维普中文科技期刊数据库(VIP)、Web of Science数据库核心集(WOS)数据库为数据资源,收集龙眼肉研究文献,导入Note Express中删除重复文献、不符合纳入标准的文献并统一关键词,利用Excel、CiteSpace 6.4.R1 advanced、VOSviewer 1.6.20软件对文献的发文量、发文国家、机构、作者、期刊、高被引频次文献、关键词等进行统计分析。结果 共检索到符合标准的文献675篇,其中中文文献605篇,英文文献70篇。龙眼肉相关研究文献的年发文量整体呈上升趋势。发文量最多的国家是中国,开展龙眼肉研究的机构也主要以中国机构为主,中、英文文献发文量最多的机构分别为山东中医药大学(11篇)和Guangdong Academy of Agricultural Science(19篇),发文量最多的作者分别为李雪华(9篇)和Zhang Mingwei(14篇),刊载量最多的期刊分别是《陕西中医》和Carbohydrate Polymers。被引频次前10的中英文文献主要研究方向为龙眼肉的临床应用及药理作用等方面,出现频次最高的中英文关键词分别为归脾汤(144次)和polysaccharides(15次)。结论 龙眼肉研究的主导力量集中在中国,尤其以中国机构为核心主体。随着国内外合作的增强、市场需求的提高、经济支撑力的提升、相关政策的引导和研究技术的进步,龙眼肉的研究已从早期的传统临床应用和经验总结,逐步发展为多学科交叉的微观分子层面的现代化研究体系。当前研究热点以传统中医药理论为基础,探究龙眼肉本身及其经典方剂(如归脾汤)的配伍机制、临床应用、化学成分以及抗氧化与抗肿瘤等药理机制。未来将继续以发扬传统中医药理论为根本,加强国际交流与文化传播,结合数字化等科技创新理念着力解决现代化中医药研究的关键技术难题,深入解析其精细化学组成与药理机制,系统揭示其药效物质基础及作用途径。同时,深化高校与企业协同合作,构建从科研到产业化的高效转化通道,推动相关成果的产业化,将传统理论与现代科技融合提升创新力和国际影响力,为龙眼肉中医药理论的现代化研究及其相关科技成果的产业化转型提供参考。
[Key word]
[Abstract]
Objective To analyze the current research status of Longyanrou (Longan Arillus) using bibliometric methods, and predict its future research hotspots and development trends. Methods Literature on Longan Arillus research was collected from the China National Knowledge Infrastructure (CNKI), Wanfang Data Knowledge Service Platform (WF), VIP Chinese Scientific Journals Database (VIP), and the Web of Science Core Collection (WOS). The retrieved literature was imported into NoteExpress, where duplicates and records not meeting the inclusion criteria were removed, and keywords were standardized. Excel, CiteSpace 6.4.R1 advanced, and VOSviewer 1.6.20 were used to statistically analyze publication volume of the literature, the countries of publication, institutions, authors, journals, literature with high citation frequency, keywords, etc. Results A total of 675 eligible articles were retrieved, including 605 Chinese articles and 70 English articles. The annual publication volume of Longan Arillus-related research showed an overall upward trend. The country with the highest publication volume is China. The institutions conducting research on Longan Arillus are also mainly Chinese institutions. The institutions with the most publications in both Chinese and English are Shandong University of Traditional Chinese Medicine (11 articles) and Guangdong Academy of Agricultural Science (19 articles), respectively. The authors with the most publications are Li Xuehua (nine articles) and Zhang Mingwei (14 articles), respectively. The journals with the highest publication volume are Shaanxi Journal of Traditional Chinese Medicine and Carbohydrate Polymers, respectively. The top 10 most cited Chinese and English articles mainly focused on the clinical application and pharmacological effects of Longan Arillus. The most frequent Chinese and English keywords were Guipi Decoction (144 times) and polysaccharides (15 times). Conclusion The dominant force in Longan Arillus research is concentrated in China, with domestic institutions serving as the core entities. With the strengthening of domestic and international collaboration, the growth of market demand, the improvement of economic support, the guidance of relevant policies, and advances in research technology, research on Longan Arillus has gradually developed from early traditional clinical application and experience summarization into a modern multidisciplinary research system at the microscopic molecular level. Current research hotspots are based on traditional Chinese medicine theory, exploring the compatibility mechanisms, clinical applications, chemical components, and pharmacological mechanisms such as antioxidation and antitumor effects of Longan Arillus itself and its classic formulas (such as Guipi Decoction). In the future, research will continue to take the promotion of traditional Chinese medicine theory as its foundation, strengthen international exchange and cultural dissemination, and integrate digital and other technological innovation concepts to address key technical challenges in modern traditional Chinese medicine research, deeply analyze the fine chemical composition and pharmacological mechanisms of Longan Arillus, and systematically reveal its pharmacodynamic material basis and pathways of action. At the same time, this study will deepen the collaborative cooperation between universities and enterprises, build an efficient transformation channel from research to industrialization, and promote the industrialization of related achievements, integrate traditional theories with modern technology to enhance innovation capabilities and international influence, and providing a reference for the modernization of traditional Chinese medicine theory on Longan Arillus and the industrialization transformation of related scientific and technological achievements.
[中图分类号]
G350;R282.71
[基金项目]
广西中医药大学“桂派中医药传承创新团队”项目(2022A005);国家药品监督管理局中药材质量监测与评价重点实验室开放课题(KFKT2022-5)