目的 基于文献计量学方法，运用CiteSpace和VOSviewer软件对国内外龙胆属领域研究现状进行可视化分析，预测其未来研究热点和发展趋势。方法 以中国知网（CNKI）和Web of Science（WOS）核心合集数据库为数据来源，检索2005年1月1日—2025年12月31日龙胆属领域的相关文献。经人工剔除重复及不符合标准文献并统一规范关键词后，利用Excel、VOSviewer及CiteSpace软件分别对龙胆属领域中英文文献的年发文量、期刊、机构、作者、国家、关键词等进行可视化分析。结果 检索得到符合要求的文献共7 449篇，其中中文文献6 121篇，英文文献1 328篇。中文文献年发文量呈波动趋势，英文文献年发文量则呈上升趋势且增势迅速，刊载龙胆属研究文献最多的中英文期刊分别是《中草药》（114篇）和Journal of Ethnopharmacology（44篇）；发文量最高的作者分别是王元忠（61篇）和Zhang Ji（27篇）；发文量最多的机构分别为黑龙江中医药大学（118篇）和Chinese Academy of Sciences（110篇）；发文量排名前3的国家分别是中国（709篇）、印度（111篇）以及日本（105篇）；通过关键词分析发现，当前研究热点主要集中于龙胆属复方分析、临床应用、物种鉴定、化学成分、药理作用和作用机制研究等方面。此外，在新冠疫情期间，含有龙胆的中药制剂也被用于治疗患者咳嗽、气喘等症状。结论 目前国内外对龙胆属领域的研究总体呈上升趋势，近年来其研究正逐步从化学成分和药理作用的单一分析转向为“多组分、多靶点”协同机制的探讨，深度融合基因组学、分子对接、网络药理学等现代技术方法，为龙胆属物种的药效机制解析及创新应用提供了重要方向。未来对于该领域的研究也可通过加强国际化协作，深化现代技术融合，从而推动龙胆属领域研究向精准化和多层次发展。

Objective CiteSpace and VOSviewer softwares were used to conduct a visualized analysis of the current status of research on Gentiana worldwide, so as to predict its future research hotspots and developmental trends based on bibliometric methods. Methods Relevant literatures on Gentiana from January 1, 2005 to December 31, 2025 were retrieved from the China National Knowledge Infrastructure (CNKI) and Web of Science (WOS) Core Collection databases. After manually excluding duplicate and ineligible literatures and standardizing keywords, Excel, VOSviewer and CiteSpace were used to perform visualized analyses on the annual publication volume, publication journals, institutions, authors, countries and keywords of Chinese and English literatures in the field of Gentiana, respectively. Results A total of 7 449 eligible literature were retrieved, including 6 121 Chinese literature and 1 328 English literature. The annual publication volume of Chinese literature showed a fluctuating trend, while that of English literature presented a rapid upward trend. The Chinese and English journals publishing the most Gentiana-related studies were Chinese Traditional and Herbal Drugs (114 publications) and Journal of Ethnopharmacology (44 publications), respectively. The authors with the highest publication outputs were Wang Yuanzhong (61 publications) and Zhang Ji (27 publications). The institutions with the largest number of Chinese and English publications were Heilongjiang University of Chinese Medicine (118 publications) and Chinese Academy of Sciences (110 publications), respectively. The top three countries in terms of the number of articles published were China (709 publications), India (111 publications), and Japan (105 publications). The keyword analysis revealed that the current research hotspots mainly focused on the analysis of compound formulations, clinical applications, species identification, chemical composition, pharmacological effects, and mechanisms of action related to the Gentiana genus. In addition, traditional Chinese medicine preparations containing Gentiana have also been used to treat symptoms such as coughing and wheezing in patients during the COVID-19 pandemic. Conclusion Research on the Gentiana genus both domestically and internationally is currently showing an overall upward trend. In recent years, studies are gradually shifting from the single analysis of chemical components and pharmacological effects to the exploration of “multi-components and multi-targets” synergistic mechanisms. This research is deeply integrating modern technological methods such as genomics, molecular docking, and network pharmacology, providing important directions for the analysis of the efficacy mechanisms and innovative applications of Gentiana-related species. Future research in this field can also promote the precision and multi-layered development of Gentiana studies by strengthening international collaboration and deepening the integration of modern technologies.

G350;R282.71

国家自然科学基金项目（32570457）；国家重点研发计划-政府间国际科技创新合作项目（2022YFE0119300）；中央高校基本科研业务费