目的 解析大戟属Euphorbia植物研究的知识演变脉络、专利谱系特征及前瞻创新方向，明确其成果转化效率与全球竞争格局。方法 采用文献计量学与知识图谱分析方法，结合专利信息谱系解析技术开展系统研究，以大戟和Euphorbia为主题词，对中国知网（CNKI）、万方（Wanfang）、维普（VIP）以及Web of Science（WOS）核心合集数据库内的相关文献进行系统检索，在NoteExpress文献管理软件中对检索到的文献进行去重、筛选和格式转换，使用CiteSpace、VOSviewer软件对中英文文献的年度发文趋势，发文国家、机构、作者及期刊载文量、学科分布等进行可视化分析。同时，基于Incopat专利数据库，从专利申请量、地域分布格局等方面系统剖析大戟属植物相关专利的申请与分布现状。结果 经筛选共纳入中文文献1 682篇，英文文献1 339篇，表明大戟属植物研究正处于国际化阶段。发文国家共98个，其中中国发表成果最多。中英文发文量最多的作者均是张丽，中英文文献的核心发文机构分别是南京中医药大学和United States Department of Agriculture，机构间的合作联系尚较分散，但部分作者之间已形成稳定研究团队。载文量最高的中英文期刊分别是《中国中药杂志》与Journal of Ethnopharmacology。英文文献涉及的学科以植物科学为主并延伸至药理学、药物化学等领域。Incopat专利数据库检索得到大戟属相关专利8 350件，国内专利5 603件，占总量的67.1%，处于主导地位。结论 大戟属植物研究呈现以中国为核心，全球参与并存的格局，该领域的基础研究体系日趋完善，传统医药应用现代化成效显著，产业转化前景广阔，但仍存在区域发展失衡等问题，后续应深耕基础理论、促进学科交叉、优化专利布局，实现资源价值高效转化与可持续开发。

Objective To analyze the knowledge evolution context, patent genealogy characteristics and prospective innovation directions of Euphorbia plant research, and clarify the efficiency of achievement transformation and the global competitive pattern, this study adopts bibliometric and knowledge graph analysis methods, combined with patent information lineage analysis technology to carry out systematic research. Methods The relevant literature in the CNKI, Wanfang, VIP and Web of Science Core Collection were systematically searched with Euphorbia pekinensis and Euphorbia as the subject words, imported into NoteExpress literature management software for deduplication, screening and format conversion, and CiteSpace and VOSviewer software were used to visualize the annual publication trends, the publishing country, institution, author, journal distribution, discipline distribution and other dimensions of Chinese and English literature. At the same time, based on the Incopat patent database, the application and distribution status of patents related to Euphorbia plants were systematically analyzed from aspects such as the number of patent applications and geographical distribution patterns. Results After the screening procedure, a total of 1 682 Chinese literature and 1 339 English literature were incorporated into the study, indicating that the research of Euphorbia plants was at the international stage. A total of 98 countries had issued documents, among which China had published the most achievements. The author with the largest number of publications in both Chinese and English was Zhang Li. The core publishing institutions of the Chinese and English literature were Nanjing University of Chinese Medicine and the United States Department of Agriculture. The cooperation connections between these institutions were still relatively scattered, but some authors had formed stable research teams. The Chinese and English journals with the highest number of articles published were China Journal of Chinese Materia Medica and Journal of Ethnopharmacology. The English literature mainly involved plant science and extended to pharmacology, medicinal chemistry and other fields. The Incopat patent database retrieved 8 350 patents related to Euphorbia plants, and 5 603 domestic patents, accounting for 67.1% of the total, which was in a dominant position. Conclusion Research on Euphorbia plants shows a pattern dominated by China, coexisting with global participation. The fundamental research system in this field has become increasingly well-established, with remarkable progress in the modernization of traditional medicinal applications and broad prospects for industrial transformation, but there are still problems such as regional development imbalance. In the future, it should deepen the basic theory, promote interdisciplinary research, optimize the patent layout, and realize the efficient transformation and sustainable development of resource value.

R282

江苏省中医疫病研究中心开放课题（JSYB2024KF28）；江苏省中医流派研究院开放课题（JSZYLP2024040）；无锡市中医药科技发展专项重点项目（ZYZD202404）；无锡市卫生健康委科技计划项目（T202549，M202329）；无锡市名中医工作室（锡中医[2023]2号〈11〉）；无锡市“双百”中青年医疗卫生拔尖人才培养计划（HB2023106）