[关键词]
[摘要]
目的 对近20年国内外滋阴中药防治肿瘤相关文献进行计量学分析,为滋阴中药防治肿瘤的药理作用和科学内涵提供参考。方法 通过检索中国知网(CNKI)、万方数据库(Wanfang Data)和Web of Science(WOS)数据库获取相关文献信息,利用NoteExpress、CiteSpace、VOSviewer、Gephi等文献计量学和可视化研究工具对筛选后文献的发文量、国家、机构、作者、关键词等进行分析,形成可视化图表结果,分析其研究现状、热点及趋势。结果 滋阴中药防治肿瘤的研究呈现逐年递增趋势,目前中文文献是该领域研究文献的主体,麦冬、石斛、枸杞子是该领域研究最多的滋阴中药。该领域研究发文量最多的国家为中国,主导力量是中国的医药类院校和医院单位。国内外作者之间均未形成核心作者群,领域研究力量呈现多元化现状。该领域研究主要集中在肺癌、有效成分、药理作用等方向,而用药规律、数据挖掘、作用机制、细胞周期调控、枸杞多糖等是近年来的研究热点。结论 滋阴中药防治肿瘤领域研究目前仍处于上升发展阶段,研究前沿聚焦于滋阴中药防治肿瘤的物质基础及作用机制、临床用药经验和方法创新等方面。
[Key word]
[Abstract]
Objective To conduct a bibliometric analysis of the relevant literature on traditional Chinese medicine with nourishing-yin properties for tumor prevention and treatment published both domestically and internationally over the past 20 years, with the intention of providing references for the pharmacological effects and scientific connotations of such traditional Chinese medicine in tumor prevention and treatment. Methods The relevant literature was obtained from the databases of China National Knowledge Infrastructure (CNKI), Wanfang Data, and Web of Science (WOS). Using bibliometrics and visualization research tools such as NoteExpress, CiteSpace, VOSviewer, and Gephi, the publication volume, countries, institutions, authors, and keywords of the selected literature were analyzed to form visualization results and analyze the current research status, hotspots, and trends. Results The analysis of publication volume shows that the research on yin-nourishing traditional Chinese medicine in tumor prevention and treatment has been increasing year by year. Currently, Chinese literature is the main body of research literature in this field. Maidong (Ophiopogonis Radix), Shihu (Dendrobii Caulis), and Gouqizi (Lycii Fructus) are the most frequently studied yin-nourishing traditional Chinese medicines in this field. The analysis of the countries and institutions that published papers indicates that the country with the most research publications in this field is China, and the dominant forces are Chinese medical colleges and hospital units. The analysis of authors’ publications shows that there is no core author group formed between domestic and international authors, and the research force in this field presents a diversified situation. The keyword analysis indicates that the research in this field mainly focuses on lung cancer, active ingredients, pharmacological effects, etc., while the medication pattern, data mining, mechanism of action, cell cycle regulation, and Lycium barbarum polysaccharides are the research hotspots in recent years. Conclusion Research on the prevention and treatment of tumors with yin-nourishing traditional Chinese medicine is still in an upward development stage at present. The research focus is on the study of the material basis and mechanism of action of yin-nourishing traditional Chinese medicines in preventing and treating tumors, as well as the research on clinical application experience and innovation in research methods.
[中图分类号]
R282
[基金项目]
中央本级重大增减支项目(2060302);国家中医药管理局科技项目(GZY-KJS-2023-021);江西中医药大学重大项目培育项目(2023ZDPY002);江西中医药大学2025年大学生创新创业训练计划项目(202510412255)