随着中药在国际上的广泛应用，其研究的标准化和国际化也逐步受到全世界专家学者的重视。但由于中药及其提取物所含化学成分的复杂性，对研究质量及研究结果的国际认可度带来挑战。通过系统地梳理中药研究应该遵守的国际最佳报告指南，包括基原、种植与采收加工、制备与提取、活性成分与质量标志物、农药残留与安全、体外与体内研究、临床研究、人工智能的使用等，旨在提升研究的可重复性及研究结果的精准诠释，从而提高研究质量与报告的透明度，为推进中药研究的标准化与国际化提供参考依据。

With the increased global demand for Chinese herbal medicines (CHM), the standardization and internationalization of CHM have been of interest to the scientific and research communities. However, there are some challenges in ensuring the quality of research and the acceptability globally since the complexity of the ingredients in CHM and their extracts. In this review, the international best practices in research reporting guidelines of CHM were summarized and discussed, including approaches to sourcing, cultivation and harvesting, extraction, preparation, bioactive constituents and quality control markers, as well as pesticide residues and safety, in vitro and in vivo studies, clinical trials, and the application of artificial intelligence. This review aims to enhance the reproducibility, and ensure precise interpretation of results, and hence, to improve research quality and transparent reporting, to facilitate the internationalization and standardization of CHM.

R28

国家自然科学基金重点项目（81630107，82330124）；国家自然科学基金面上项目（82274155，8257141424，82274176）；湖北省中医药管理局中医药重大项目（ZY2025Z019）；湖北省科技创新平台专项（2025CSA097）；武当特色中药研究湖北省重点实验室开放课题（WDCM2024032）