病毒性肝炎是全球严重的流行病，甲型、乙型、丙型、丁型和戊型肝炎病毒均可能导致肝损伤、肝硬化甚至是肝癌的发生；且每种病毒性肝炎均可能有黄疸的临床表现，而黄疸在我国早已有应用中医药治疗的临床经验。尽管现代抗病毒性肝炎药物多样且疗效确切，但其在治疗过程中存在耐药性、易复发及不良反应多等局限；中药因其多成分、多靶点和多途径的特点，在抗病毒性肝炎领域具有独特优势。目前已有研究表明中药复方、单味药及其活性成分可通过干预病毒入侵、抑制病毒复制和调节肝脏微环境等途径发挥抗病毒性肝炎的作用。中药在抗病毒性肝炎领域具有广阔的应用前景，有望为新型抗病毒性肝炎治疗策略的开发提供重要参考。

Viral hepatitis is a serious global epidemic. Hepatitis viruses A, B, C, D, and E can all cause liver damage, cirrhosis, and even liver cancer; each type of viral hepatitis may present with jaundice, and jaundice has long been treated with traditional Chinese medicine in clinical practice in China. Although modern antiviral drugs for hepatitis are diverse and effective, their use is limited by drug resistance, easy recurrence, and multiple adverse reactions. Traditional Chinese medicine, due to its characteristics of multiple components, multiple targets, and multiple pathways, has unique advantages in the field of antiviral hepatitis. Current research has shown that Chinese medicine formulations, single herbs, and their active components can exert antiviral hepatitis effects by intervening in viral invasion, inhibiting viral replication, and regulating the liver microenvironment. Traditional Chinese medicine has broad application prospects in the field of antiviral hepatitis and is expected to provide important references for the development of new antiviral hepatitis treatment strategies.

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国家自然科学基金资助项目（82204656）；博士后科学基金特别资助（2024T170534）；山东省中医药科技项目（M20241725）；山东中医药大学青年创新团队支持计划（22202105）；山东省大学生创新创业训练计划（S202510441007）