酸枣仁汤出自东汉末年张仲景所著的《金匮要略》，由酸枣仁、甘草、知母、茯苓、川芎组成，具有养血安神、清热除烦等功效，主治肝血不足、虚热内扰证。近年来，酸枣仁汤的药理作用机制的研究主要集中在催眠镇静、抗焦虑抑郁、神经保护等神经系统及保护心肌、抗炎等方面。临床上，常用于治疗失眠症、焦虑症、抑郁症及心血管系统等疾病，疗效显著。通过对酸枣仁汤的药理作用和临床应用进行综述，为酸枣仁汤的进一步研究提供参考。

Suanzaoren Decoction, originated from the Synopsis of Golden Chamber written by Zhang Zhongjing in the late Eastern Han Dynasty, is composed of Suanzaoren (Ziziphi Spinosae Semen), Gancao (Glycyrrhizae Radix et Rhizoma), Zhimu (Anemarrhenae Rhizoma), Fuling (Poria) and Chuanxiong (Chuanxiong Rhizoma). It has the effects of nourishing blood and calming the mind, clearing heat and eliminating irritability. In recent years, the research on the pharmacological mechanism of Suanzaoren Decoction mainly focuses on the aspects of hypnosis, sedation, anti-anxiety and depression, neuroprotection and other aspects of nervous system, myocardium protection and anti-inflammatory. Clinically, it is widely used to treat insomnia, anxiety, depression, and cardiovascular diseases with notable efficacy. In this paper, the pharmacological action and clinical application of Suanzaoren Decoction were reviewed in order to provide reference for the further study of Suanzaoren Decoction.

R285

国家自然科学基金资助项目（82274316）；河南省高等学校重点科研计划项目（23A320065）；河南省医学教育研究项目（WJLX2023212）