糖尿病心肌病（diabetes cardiomyopathy，DCM）是糖尿病患者的常见并发症之一，根据病情严重程度可表现为心肌病变、心室结构异常、心脏功能不全，乃至心力衰竭等，严重威胁患者生命安全。其中糖尿病心肌纤维化（diabetic myocardial fibrosis，DMF）是DCM由中度向重度转变的重要标志，因此防治DMF，对避免DCM引起的患者死亡具有重要意义。现代中医将DCM归类于“消渴”兼具“胸痹”“胸痛”“心痛”“心悸”等证，并尝试从中医药角度防治DMF。通过对近20年中药防治DMF的相关研究进行归纳总结，为DMF的研究与治疗提供参考。

Diabetes cardiomyopathy (DCM) is a main cardiovascular complication of diabetes. It can develop into cardiomyopathy, abnormal ventricular structure, cardiac insufficiency and even heart failure. Diabetic myocardial fibrosis (DMF) is the main factor causing ventricular wall stiffness and heart failure in DCM. Thus, blocking DCM progression to DMF is crucial. Consumptive thirst was the understanding of diabetes in traditional Chinese medicine, while, consumptive thirst accompanied by thoracic obstruction, cardiodynia, or palpitation is similar to DMF. In this paper, we summarized the research progress in recent 20 years, in order to provide reference for research and treatment of DMF.

R285

山东省重大科技创新工程项目（2021CXGC010508）