心血管疾病（cardiovascular diseases，CVDs）作为一类全球多发疾病，其预防与治疗长期受到高度关注。尽管传统治疗方法如药物治疗、外科手术和介入疗法在CVDs治疗领域取得显著进展，但高昂的费用、明显的不良反应及复杂的药物间相互作用等问题仍亟待解决。氧化应激是CVDs发展的关键因素，有效缓解氧化应激反应为寻找新的治疗策略提供了思路。植物精油作为一种天然抗氧化剂，因其独特的生物活性和较低的毒性，在CVDs的预防和治疗中展现出巨大潜力。通过对植物精油相关活性成分在CVDs治疗中的抗氧化机制及其研究进展进行综述，为植物精油作为CVDs辅助治疗提供科学依据，并推动其临床应用。

The prevention and treatment of cardiovascular diseases (CVDs), as a group of globally prevalent diseases, have long received great attention. Although conventional therapies, such as pharmacotherapy, surgery and interventional therapy, have made significant progress in treatment of CVDs, high costs, significant adverse effects and complex drug-drug interactions still need to be addressed. Oxidative stress is a key factor in the development of CVDs, and effective mitigation of oxidative stress provides ideas for finding new therapeutic strategies. As a natural antioxidant, plant essential oils show great potential in prevention and treatment of CVDs due to their unique bioactivity and low toxicity. By reviewing the antioxidant mechanisms of plant essential oil-related active ingredients in treatment of CVDs and their research progress, this review provides a scientific basis for the use of plant essential oils as an adjunctive therapy for CVDs and promote their clinical application.

R285

国家自然科学基金资助项目（31760099）