目的 借助文献计量学软件CiteSpace，全面分析中医药防治卵巢衰老的研究现状与热点，为未来基础研究和临床应用提供新的思路与方向。方法 构建主题相关检索式，在中国知网（CNKI）和Web of Science核心合集数据库（WOScc）检索目标文献，将文献导入Note Express软件进行文献查重和数据清洗，结合Microsoft Excel软件，对发文趋势、发文核心期刊、发文作者和机构以及关键词进行可视化分析。结果 根据纳入和排除标准，筛选获得文献2 764篇，包括中文文献2 569篇、英文文献195篇。中医药防治卵巢衰老的热度呈逐年上涨趋势并延续至今，发文类型逐渐向国际化趋势发展。中医药防治卵巢衰老领域的核心作者团队已初步建立，但尚未形成核心作者群，且研究合作以机构内和区域内为主，跨区域和跨学科的合作较少。中、英文文献均重点关注了中医药防治卵巢衰老的生殖功能恢复、中医药治疗、作用机制、实验模型等方面。中文文献还注重临床观察、病因病机、用药规律等方面研究，英文文献还注重网络药理学、基因表达、代谢和细胞等方面研究。结论 中医药防治卵巢衰老的研究热度逐年增长，作用机制、数据挖掘、网络药理学、分子对接可能是今后该领域研究的趋势。中医药疗法、作用机制和研究技术方法等研究方向是近年来中医药防治卵巢衰老的研究热点。未来研究应加强不同区域团队交流和交叉学科团队合作，不断融合现代科技新技术，科学、全面地阐明中医药防治卵巢衰老的疗效和作用机制，促进中医药防治卵巢衰老理论和应用的发展，推进成果产出效率与质量，提高中医药现代化水平。

Objective To comprehensively analyze the current research status and hotspots of traditional Chinese medicine (TCM) in the prevention and treatment of ovarian aging using the bibliometric software CiteSpace, and to provide new ideas and directions for future basic research and clinical applications. Methods Relevant search queries were constructed to retrieve target literature from the CNKI and Web of Science Core Collection (WOScc) databases. The retrieved literature was imported into Note Express software for duplicate checking and data cleaning. Visualization of publication trends, core journals, authors, institutions, and keywords was conducted using Microsoft Excel software. Results According to the inclusion and exclusion criteria, a total of 2 764 articles were selected, including 2 569 Chinese articles and 195 English articles. The research interest in TCM for the prevention and treatment of ovarian aging has been increasing annually and continues to this day, with publication types gradually trending towards internationalization. A core author team in the field of TCM for the prevention and treatment of ovarian aging has been initially established, but a core author group has not yet formed. Research collaboration is primarily within institutions and regions, with less cross-regional and interdisciplinary collaboration. Both Chinese and English literature focus on the restoration of reproductive function, TCM treatment, mechanisms of action, and experimental models in the prevention and treatment of ovarian aging with TCM. Chinese literature also emphasizes research on clinical observations, etiology and pathogenesis, and medication patterns, while English literature focuses on network pharmacology, gene expression, activation, metabolism, and cellular aspects. Conclusion The research interest in TCM for the prevention and treatment of ovarian aging has been growing annually. The mechanisms of action, data mining, network pharmacology, and molecular docking are likely to be future research trends in this field. Research directions such as TCM therapies, mechanisms of action, and research technical methods have been hot topics in recent years. Future research should strengthen communication among teams from different regions and interdisciplinary team collaboration, continuously integrate new technologies from modern science and technology, scientifically and comprehensively elucidate the efficacy and mechanisms of action of TCM in the prevention and treatment of ovarian aging, promote the development of theories and applications of TCM in this field, enhance the efficiency and quality of research outcomes, and improve the modernization level of TCM.

G350;R285

湖南省自然科学基金青年基金项目（2025JJ60625）；湖南省卫生健康委员会科研计划课题（C202305016294）；湖南省教育厅科学研究项目（23A0306）；湖南省卫生健康委员会科研课题（W20243198）；湖南中医药大学校院联合基金重点项目（2023XYLHJJ005）；湖南中医药大学校院联合基金一般项目（Z2023XJYB21）