伤口修复是一个包括止血、炎症、增殖和重塑等多个阶段的过程，传统及现有部分治疗方法对复杂伤口效果有限。中药多糖具有促进伤口修复的潜力，其来源广泛，化学结构多样，具有免疫调节、抗氧化、抗炎、促修复、细胞调节等多重药理作用，具有良好的临床应用潜力。基于近年来国内外伤口修复的研究现状，对其主要生理过程及中药多糖的物质基础进行综述，为中药多糖促进伤口修复的作用机制及新药研发提供参考。

Wound repair is a process encompassing multiple stages, including hemostasis, inflammation, proliferation, and remodeling. Conventional and some existing therapeutic approaches have limited effectiveness in treating complex wounds. Polysaccharides derived from traditional Chinese medicine (TCM) possess the potential to promote wound repair. They have a wide range of sources and diverse chemical structures, and exhibit multiple pharmacological effects such as immunomodulation, antioxidant activity, anti-inflammation, promotion of repair, and cell regulation, thus showing promising potential for clinical application. Based on the current research status of wound repair both at home and abroad in recent years, this article reviews the main physiological processes of wound repair and the material basis of TCM polysaccharides, with the aim of providing a reference for the mechanism of action of TCM polysaccharides in promoting wound repair and the research and development of new medicines.

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上海市卫生健康委员会中医药科研项目（2024QN057）；军队后勤科研项目（BHJ22J020）；海军重点学科专业群建设项目（2024-HJZDXK-JS-12，2024-HJZDXK-SZ-01）；国家重点研发计划资助项目（2022YFC3502000）；国家自然科学基金资助项目（82430119，82173704）；海军军医大学“深蓝”工程启航人才计划；海军军医大学教学成果立项培育项目（JPY2024B06）