肉苁蓉Cistanches Herba为我国传统大宗药材，临床应用广泛，素有“沙漠人参”之称。已在2023年通过食用安全性评价，正式被国家卫生健康委员会列入药食同源物质目录。研究发现，肉苁蓉属植物富含多糖、有机酸、蛋白质、膳食纤维、矿质元素、氨基酸、维生素等初生代谢成分，及苯乙醇苷类、环烯醚萜苷类、木脂素类等次生代谢成分，具有神经保护、润肠通便、免疫调节、益肾保肝、抗骨质疏松、抗肿瘤、抗炎、抗氧化等药理活性。通过对肉苁蓉属植物的初生代谢成分、次生代谢成分、药理活性及药食两用等进行综述，为肉苁蓉活性成分的临床应用、药食同源开发及生物资源的综合利用提供参考。

Roucongrong (Cistanches Herba), a traditional Chinese medicinal material with extensive clinical applications, is known as the “Ginseng of the Desert”. In 2023, it has passed the evaluation of food safety and has been officially included in the directory of substances that are the same origin as food and medicine by the National Health Commission of China. It has found that plants of genus Cistanche are rich in a variety of primary metabolites, such as polysaccharides, organic acids, proteins, dietary fiber, mineral elements, amino acids, and vitamins, as well as secondary metabolites like phenylethanoid glycosides, iridoid glycosides, and lignans, etc. These compounds exhibit a range of pharmacological activities, including neuroprotection, moistening the intestines and relieving constipation, immune regulation, kidney and liver protection, anti-osteoporosis, anti-tumor, anti-inflammatory, and antioxidant effects. The primary metabolites, secondary metabolites, pharmacological activities and dual-use of Cistanchis plants were systematically reviewed in order to provide references for the clinical application, the development of medicine and food homology, and the comprehensive utilization of biological resources of Cistanches Herba active ingredients.

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甘肃省科技计划项目（20JR10RA355）；甘肃省卫生健康行业科研项目（GSWSKY2022-27）；国家中医优势专科建设项目—脑病临床医学中心（甘卫中医函[2023]63号）