党参Codonopsis Radix为桔梗科植物党参C. pilosula、素花党参C. pilosula var. modesta与川党参C. tangshen的干燥根，属药食同源植物。党参作为典型的补益类中药，具有悠久的药用历史，在临床应用上广泛。党参多糖是党参中最重要的活性化合物之一，具有抗肿瘤、增强免疫、抗炎、抗氧化、神经保护、肝保护、抗骨质疏松、抗肥胖、促进伤口愈合、肺保护、抗衰老以及其他等多种生物活性，已经成为党参药材开发应用研究的热点，具有很高的药用价值和经济价值。综述了近3年来国内外对党参多糖制备技术、结构特征、生物活性及其作用机制和药代动力学研究进展，以期为党参多糖在工业制药和功能性食品领域的深入研究与开发奠定理论基础。

The Chinese herb Dangshen (Codonopsis Radix), which is the dried root of C. codonopsis, C. pilosula var. modesta and C. tangshen, which belongs to food and medicine homology herb in family Campanulaceae. As a typical tonic Chinese medicine, Codonopsis Radix has a long medicinal history and is widely used in clinic. C. pilosula polysaccharides (CPPs) are one of the most important and most representative active compounds in Codonopsis Radix, which exhibites diverse bioactivities such as anti-tumor, immune enhancement, anti-inflammation, anti-oxidant, neuroprotection, hepatoprotection, anti-osteoporosis, anti-obesity, wound healing promotion, lung protection, anti-aging and other activities. It has became a hot spot in the development and application of Codonopsis Radix, and has high medicinal and economic value. In this paper, the preparation technologies, structural characteristics, bioactivities, mechanism of action and pharmacokinetics of CPPs at home and abroad in the past three years were reviewed, in order to lay a theoretical foundation for further research and development of CPPs in the field of industrial pharmaceutical and functional food.

R286.2

陕西省科技计划项目（2021ZDLSF04-09）；陕西国际商贸学院校级课题（SMXY202217）