五味子Schisandra chinensis是木兰科五味子属药用植物，干燥成熟的果实是其药用部位。五味子的主要活性成分包括木脂素、多糖、挥发油等，具有多种药理作用。系统总结五味子上市药品的研究现状与进展，包括五味子药品的生产工艺、质量标准、临床研究及药理作用等方面，同时关注五味子上市药品及相关制品的再开发。现有五味子药品存在品种单一、临床定位不清晰、质量控制技术亟待提升等问题。未来需进一步明确其临床应用定位，优化质量标准和控制技术，推动其国际化发展，从而提升五味子药品的临床价值与市场竞争力。

Schisandra chinensis (Turcz.) Baill. is a kind of medicinal plant, which belongs to the family of Magnoliaceae, Schisandra. Its medicinal part is the dried ripe fruits. The main bioactive components of S. chinensis, including lignans, polysaccharides, and volatile oils, exhibit various pharmacological effects. This review systematically summarized the current state and research progress of commercial pharmaceutical products of S. chinensis. The production processes, quality standards, clinical research and related pharmacological effects of these products were analyzed. We also focused on the redevelopment of these commercial products and related products. The existing drugs face issues such as limited variety, unclear clinical orientation, and the need for improvements in quality control techniques. In the further, it is necessary to clarify the clinical application orientation, optimize quality standards and control techniques, and promote international development to enhance the clinical value and market competitiveness of S. chinensis products.

R282.71

广州市科技计划项目基础与应用基础研究专题（2023A04J1101）;国家自然科学基金青年基金（82104095）;广东省科技厅与澳门科学技术发展基金联合科研资助项目（0012/2022/AGJ）