目的 真菌是我国独特的优势资源，多糖是真菌最主要的活性成分之一，选取5种广泛应用的真菌多糖，基于Citespace全面分析该研究领域的发展现状、研究热点与前沿趋势，并浅析真菌多糖发展的薄弱环节，为未来该领域的科学研究和产业发展提供参考。方法 利用中国知网、万方、维普以及Web of Science数据库，以“香菇多糖”“灵芝多糖”“灰树花多糖”“黑木耳多糖”“虫草多糖”为关键词检索相关文献，通过NoteEpress去重合并，使用Citespace 6.2 R4软件对其作者、机构、关键词等进行可视化分析和内涵解读。结果 5种真菌多糖领域的研究主要以中国学者和科研机构为主，研究方向主要围绕提取工艺、结构表征、药理活性3个热点方面展开。然而目前真菌多糖仍缺乏潜在药效机制的探索创新并存在临床验证、质量评控等薄弱环节。结论 真菌多糖的研究与开发是助力大健康产业高质量发展的内容之一，应进一步加强多学科领域交叉与合作，攻克薄弱环节，提升真菌多糖在医药、食品、农业等领域的重要应用价值。

Objective Fungi are a unique and advantageous resource in China. Polysaccharides are one of the most important active ingredients in fungi. A total of five widely used fungal polysaccharides were selected and based on Citespace, comprehensively analyzed the development status, research hotspots and frontiers of fungal polysaccharide research, and briefly analyzed the weak links in the development of fungal polysaccharides to provide reference for future scientific research and industrial development in this field. Methods By using Chinese databases (CNKI, Wanfang, VIP) and Web of Science (WOS), relevant literature with keywords as “lentinan”, “Ganoderma lucidum polysaccharide”, “Grifola frondosa polysaccharide”, “Auricularia auricula polysaccharide” and “Cordyceps polysaccharide” was retrieved. After deduplication and format conversion by NoteExpress, Citespace 6.2 R4 software was used for visual analysis and connotation interpretation of the authors, institutions, and keywords. Results The research field of fungal polysaccharides is mainly led by Chinese scholars and scientific research institutions, with research directions mainly focusing on three hotspots such as extraction technology, structural characterization, and pharmacological activity. However, there is still a lack of exploration and innovation in the potential pharmacological mechanisms, clinical verification, and quality control of fungal polysaccharides. Conclusion The research and development of fungal polysaccharides are one of the important contents to promote the high-quality development of the great health industry. It is necessary to further strengthen the intersection and cooperation in multidisciplinary fields, overcome weak links, and enhance the important role of fungal polysaccharides in the fields of medicine, food, and agriculture.

R914

黑龙江省重点研发计划指导类项目资助（GZ20210088）;哈尔滨市科技创新人才项目（2022CXRCCG013）;黑龙江省双一流学科协同创新成果项目（LJGXCG2023-039）;哈尔滨商业大学产业化项目（22CZ13）