目的 利用CitySpace对沙棘多糖的中英文文献进行计量学分析，探究沙棘多糖的研究进展与未来研究热点。方法 利用Web of Science数据库和中国知网（CNKI）数据库检索1997—2024年发表的与沙棘多糖研究相关的文献，使用CiteSpace对其发文量、作者、发文机构、发文期刊、资助基金、关键词、文献被引频次等进行可视化分析。根据可视化结果探讨沙棘多糖的研究概况与未来发展趋势。结果 共检索到文献165篇，其中中文文献135篇，英文文献30篇。2021年中文文献发表量最高，为22篇，而英文文献发表量最高在2023年，为7篇，中文文献发表量远多于英文。发文机构中，新疆农业大学和内蒙古农业大学发文量最高；发表沙棘多糖文献最多的中英文期刊分别是《食品工业科技》与International Journal of Biological Macromolecules；对沙棘多糖进行研究资助的资金主要来自国家自然科学基金；关键词分析显示，沙棘多糖近几年的研究热点主要在多糖提取、结构表征、抗氧化、肝损伤、肠道菌群、炎症等方面；引用频次最高的文献主要研究内容为提取纯化、抗氧化、肝损伤等方面。结论 沙棘多糖的年发文量呈现增长趋势，在国家自然科学基金与地方资金的资助下，以新疆农业大学及内蒙古农业大学为首的高校、科研机构的研究人员对沙棘多糖展开了大量研究。沙棘多糖的研究热点集中在多糖提取纯化、抗氧化、肠道菌群、炎症、自噬、神经保护等方面，预测未来研究热点将主要围绕沙棘多糖药理活性与肠道菌群之间的作用机制及相关信号通路。深入探究沙棘多糖的药理作用及其临床应用，以及在动物医学领域的应用，为推动沙棘多糖新型功能性食品和医药产品的研发奠定坚实的基础。

Objective To explore the history and future research hotspots of Hippophae rhamnoides polysaccharides (HRPs) by adopting CitySpace to conduct a metrological analysis of Chinese and English literature on HRPs. Methods Web of Science core collection database and China National Knowledge Internet (CNKI) database were adopted to retrieve published literatures related to HRPs from 1997 to 2024. Meanwhile, CiteSpace software was conducted to visually analyze the number of publications, authors, publishing institutions, publishing journals, funding, keywords and citation frequency. According to the visualization results, the research status and future development trends of HRPs were discussed. Results A total of 165 Chinese and English articles have been retrieved, of which 135 in Chinese and 30 in English literatures. The highest number of published Chinese literatures is 22 in 2021, while that of English papers is seven in 2023. The number of published Chinese literatures is much more than that in English articles. Among the publishing institutions, Xinjiang Agricultural University and Inner Mongolia Agricultural University have the highest number of publications. Additionally, the Chinese and English journals possessing the highest articles on HRPs are Science and Technology of Food Industry and International Journal of Biological Macromolecules, respectively. The main funding for the research on HRPs comes from the National Natural Science Foundation of China. Key words analysis reveals the research focus of HRPs in recent years is mainly extraction, structural characterization, antioxidation, liver injury, intestinal flora, inflammation and so on. The most frequently cited literatures is concentrating on extraction and purification, antioxidation, liver injury and so on. Conclusion The annual published volume of HRPs demonstrates an increasing trend. With the support of National Natural Science Foundation of China and local funds, researchers from universities and research institutions led by Xinjiang Agricultural University and Inner Mongolia Agricultural University have carried out a lot of research on HRPs. The research hotspot of HRPs concentrates upon the extraction and purification of polysaccharide, antioxidation, regulation of intestinal flora, inflammation, autophagy, and neuroprotection. It is predicted that future research hotspots will mainly focus on the mechanism of action and related signaling pathways between the pharmacological activities and intestinal flora of HRPs. Exploreing pharmacological effects and clinical trials of HRPs, as well as the application in the field of animal husbandry and medicine, will lay a solid foundation for promoting the research and development of new functional food and pharmaceutical products of HRPs.

G350;R282.7

黑龙江省双一流学科协同创新成果项目(LJGXCG2023-039);黑龙江省省属高等学校基本科研业务费项目资助(2020CX38,2023-KYYWF-1088);黑龙江省中医药科研项目(ZYW2022-093);哈尔滨市创新人才项目(2022CXRCCG013);中央引导地方科技发展专项项目(ZY2022B-HRB-12)