[关键词]
[摘要]
目的 白术Atractylodis Macrocephalae Rhizoma作为传统中药材,近年来在健康产品开发和临床应用方面受到广泛关注。旨在通过可视化分析方法探索白术研究的现状、热点和前沿趋势,为其深度开发和应用提供科学依据。方法 基于CNKI和Scopus数据库,收集有关白术研究的中英文文献,利用VOSviewer和CiteSpace软件进行文献计量学分析,重点关注出版年份、国家、研究机构、期刊、作者以及关键词等方面。结果 白术研究涉及多个国家和地区,其中中国在该领域的研究贡献最为突出。研究热点集中在白术的活性成分提取、药理作用机制、网络药理学和分子对接等方面,白术多糖、脂多糖和氧化应激等关键词成为研究的新兴热点,预示着未来研究的趋势。结论 白术的研究热情持续增长,中国在该领域发挥着重要作用,但国家合作和机构合作有所欠缺,建议加强国际合作和机构间的交流,以促进白术研究的深入发展。目前的研究重点在于白术活性成分的探索和药理机制的研究,同时网络药理学和分子对接在白术领域的应用是较为新颖的主题,未来将更加注重健康产品的开发和临床应用。
[Key word]
[Abstract]
Objective As a traditional Chinese herbal medicine, Baizhu (rhizome of Atractylodes macrocephala, AM) has received extensive attention in recent years in terms of health product development and clinical application. To explore the current status, hotspots and cutting-edge trends of AM research through visual analytical methods, so as to provide a scientific basis for its in-depth development and application. Methods Based on CNKI and Scopus databases, Chinese and English literature on AM research were collected, VOSviewer and CiteSpace software were used for bibliometric analysis, focusing on publication year, country, research institution, journal, author and keywords. Results AM research involved several countries and regions, among which China had made the most outstanding research contribution in this field. The research hotspots focused on the extraction of active ingredients of AM, pharmacological mechanism of action, network pharmacology and molecular docking, etc. The keywords of AM polysaccharides, lipopolysaccharides and oxidative stress became the emerging hotspots of the research, which foreshadowed the trend of future research. Conclusion Research interest in AM continues to grow, with China playing an important role in the field, but national cooperation and institutional collaboration are lacking, and it is recommended that international cooperation and inter-institutional exchanges be strengthened in order to promote in-depth development of AM research. Current research focuses on the exploration of the active ingredients and pharmacological mechanisms of AM, while the application of network pharmacology and molecular docking in the field of Atractylodes macrocephala is a relatively novel topic, with more emphasis on the development of health products and clinical applications in the future.
[中图分类号]
G350;R282.71
[基金项目]
国家重点研发计划项目(2022YFC3501705);国家自然科学基金面上项目(82274066);上海市领军人才计划(SHLJ2019100);上海中医药大学科技发展项目(23KFL046)