[关键词]
[摘要]
目的 通过对近10年来有关中药快速分析检测技术的相关文献进行分析研究,探讨中药快速分析检测技术领域的研究热点与发展趋势。方法 在中国知网(CNKI)、万方、维普和Web of Sicence(WOS)数据库中检索与中药快速分析检测技术相关的中英文文献,并使用CiteSpace软件对文献数量、国家、机构、作者合作网络,以及关键词共现、时区聚类、突现进行可视化分析。结果 最终纳入符合要求的中文文献987篇,英文文献1 331篇,总发文量呈增长趋势;发文量最多的国家依次为中国、美国、澳大利亚和日本。中文文献重点关注中药质量控制与质量评价的快速分析检测技术,涵盖了诸多与中药质量相关的研究内容,关注各种新型技术的开发和研究;英文文献侧重于对化学成分和药理学的研究,尤其是对质谱技术和近红外光谱技术的深层次研究。中文文献涉及的快速分析检测技术较多,倾向于新型检测技术的开发,如光谱技术、仿生技术、分子鉴定和传感器检测等,这些技术在中药领域的应用为中药的深度研究和实际生产提供了良好的技术支持。结论 通过可视化图谱直观展示了近10年来中药快速分析检测领域的研究概况,揭示了该领域的研究逐渐深入,发展趋势良好的特点。然而,目前对中药快速分析检测技术的研究主要集中在新型检测技术的开发与应用,需要加大研发力度,注重科研成果的转化并与生产实际紧密连接。同时,也需要打破合作壁垒,充分展现各个研究方向的优势,加深研究层次。强调传统技术与现代科学技术的融合,实现不同仪器间性能的互补,以突破分析检测难点,从而更好地实现快速分析检测技术的价值,推动中药快速分析检测技术的创新与进步。
[Key word]
[Abstract]
Objective Based on the analysis and research on the related literature of rapid analysis and detection technology of traditional Chinese medicine in recent 10 years, the research hotspots and development trends in the field of rapid analysis and detection technology of traditional Chinese medicine were discussed. Methods In CNKI, Wanfang, VIP and Web of Sicence(WOS) databases, Chinese and English academic literatures related to the field of rapid analysis and detection technology of traditional Chinese medicine were retrieved, and the number of published literatures, countries (regions), institutions, cooperative networks of authors, co-occurrence, time zone clustering and emergence of keywords were visually analyzed by CiteSpace software. Results Finally, a total of 987 Chinese documents and 1331 English documents were included, and the total number of articles published showed an increasing trend. The countries (regions) with the largest number of articles are China, the United States, Australia and Japan. Chinese literature focuses on the rapid analysis and detection technology of quality control and evaluation of traditional Chinese medicine, covering many research contents related to the quality of traditional Chinese medicine, and paying attention to the development and research of various new technologies. English literature focuses on the study of chemical constituents and pharmacology, especially on in-depth study of mass spectrometry and near infrared spectroscopy. In Chinese literature, there are many rapid analysis and detection technologies involved, which tend to develop new detection technologies, such as spectroscopy, bionic technology, molecular identification and sensor detection. The application of these technologies in the field of traditional Chinese medicine provides good technical support for the in-depth research and actual production of traditional Chinese medicine. Conclusion Through the visual atlas, the general situation of the research in the field of rapid analysis and detection of traditional Chinese medicine in recent 10 years is intuitively displayed, and the characteristics of gradual deepening and good development trend in this field are revealed. However, at present, the research on the rapid analysis and detection technology of traditional Chinese medicine mainly focuses on the development and application of new detection technology, which needs to strengthen research and development, pay attention to the transformation of scientific research results and closely connect with production practice. At the same time, it is also necessary to break the barriers of cooperation, fully display the advantages of various research directions, and deepen the research level. Emphasis is placed on the integration of traditional technology and modern science and technology, and realize the complementary performance of different instruments, so as to break through the difficulties of analysis and detection, thus better realizing the significance of rapid analysis and detection technology, and promoting the innovation and progress of rapid analysis and detection technology of traditional Chinese medicine.
[中图分类号]
G350;R284
[基金项目]
杭州市农业与社会发展科研重点项目(202204A06);国家中医药管理局科技司-浙江省中医药管理局共建科技计划项目(GZY-ZJ-KJ-24040);浙江中医药大学中药饮片有限公司科技创新项目(2022ZZKY001)