目的 研究温度对中药浸膏粉吸湿动力学过程的影响，为中药制备、储存过程中温度控制提供理论依据。方法 选择13种中药浸膏粉，利用动态水分吸附仪在相对湿度75%，温度20、30、40 ℃下测定吸湿动力学数据，利用动力学模型拟合吸湿过程的动力学曲线，分析温度对吸湿动力学的影响。结果 双指数模型为最佳拟合模型，升高温度可以明显降低平衡吸湿量（equilibrium moisture content，EMC），加快吸湿速度，减少达到吸湿平衡的时间。结论 在浸膏粉生产和储存过程中，温度是影响其稳定性的关键因素之一，因此需要严格控制环境温度，减缓中药浸膏粉储存过程中吸湿。

Objective To explore the effect of temperature on the hygroscopic kinetic process of traditional Chinese medicine (TCM) extract powder, the theoretical basis for temperature control during the preparation and storage process of TCM. Methods The moisture absorption kinetics data of 13 kinds of TCM extract powder were measured by dynamic moisture adsorption instrument at relative humidity of 75% and temperature of 20, 30, and 40 ℃. The kinetic curve of moisture absorption process was fitted by kinetic model, and the influence of temperature on moisture absorption kinetics was analyzed. Results The double exponential model is the best fit model. Increasing the temperature can significantly reduce the equilibrium moisture content (EMC), accelerate the moisture absorption rate, and reduce the time to reach the moisture absorption balance. Conclusion During the production and storage of extract powder, temperature is one of the key factors affecting its stability. Therefore, it is necessary to strictly control the ambient temperature to slow down the moisture absorption during the storage of TCM extract powder.

R283.6

江西省重点研发计划项目:中药配方颗粒干法制粒技术智能化开发( S2021ZPYFB0258);国家药品监督管理局药物制剂技术研究与评价重点实验室开放项目：中药固体制剂干法制粒关键技术研究(2023TREDP01);江西省卫生计生委中医药科研课题( 2014A012)