桑椹Mori Fructus是使用历史悠久的药食两用中药，有滋阴补血及生津润燥之功效。现代研究表明桑椹主要含有黄酮、酚酸、生物碱、苯丙素、苯并呋喃、萜类及多糖等化学成分。药理学研究证实其主要具有调血脂、抗糖尿病、保肝、抗氧化、抗衰老、神经保护、免疫调节、抗炎、抗肿瘤、骨保护及抗便秘等作用。通过对近年来国内外关于桑椹化学成分和药理作用研究报道进行总结，为桑椹药用价值的深入挖掘和相关产品的开发提供参考。

Sangshen (Mori Fructus) is an edible and medicinal homologous traditional Chinese medicine with a long history of use. It has the efficacies of nourishing yin, tonifying blood, generating fluids and moistening dryness. Modern phytochemical studies have shown that Mori Fructus mainly contains flavonoids, phenolic acids, alkaloids, phenylpropanoids, benzofurans, terpenoids and polysaccharides, etc. Pharmacological studies have shown that it mainly possesses the biological activities of regulating blood lipids, anti-diabetes, liver protection, anti-oxidation, anti-aging, neuroprotection, immune regulation, anti-inflammation, antitumor, bone protection and anti-constipation, etc. This paper summarizes the research reports on the chemical constituents and pharmacological effects of Mori Fructus, in order to provide reference for the in-depth excavation of the medicinal value and the development of related products of Mori Fructus.

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西南民族大学中央高校基本科研业务费专项（ZYN2024035）；西南民族大学大学生创新创业训练计划项目（202310656009）