药用植物是中药的原材料之一，其品质高低是中医药产业保持活力的根源。以往研究强调道地产区、生态环境及基因型对中药材产量的影响，而近几年植物微生物组研究的发展为提升药用植物品质提供了新思路，内生菌与根际微生物对药用植物的作用受到广泛关注。科学合理利用药用植物-内生菌-根际微生物三者互作的原理，对促进药用植物生长、提高药用植物品质、消除连作障碍等具有重要意义。通过对近年来药用植物与内生菌及根际微生物的研究现状进行综述，为深入了解内生菌、根际微生物与药用植物间的三者互作关系提供参考。

Medicinal plants are one of the raw materials of traditional Chinese medicine (TCM), and their quality is the root of the TCM industry to maintain its vitality. Previous studies have emphasized the influence of local production areas, ecological environments and genotypes on the yields of Chinese medicinal plants, while the development of plant microbiome research in recent years has provided new ideas to enhance the quality of medicinal plants, and the roles of endophytic bacteria and rhizosphere microbes on medicinal plants have received widespread attention. The scientific and rational utilization of the principle of medicinal plants-endophytic fungi-rhizosphere microbes interactions is of great significance in promoting the growth of medicinal plants, improving the quality of medicinal plants and eliminating the barriers of continuous cultivation. By reviewing the current status of research on medicinal plants, endophytic fungi and rhizosphere microbes in recent years, this study can provide a reference for the in-depth understanding of the triple interactions between endophytic fungi, rhizosphere microbes and medicinal plants.

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山东省科技攻关项目（2010GSF275）；山东省教育厅科研项目（J08LH10）；国家中医药管理局全国中药资源普查资助项目（GZY-KJS-2018-004）；山东省重点产业关键技术资助项目（2016CYJS08A01-8）；山东省中医药管理局中医药科技发展计划资助项目（2019-0976）