中药网络药理学作为一门从系统层面揭示中药与机体关系的新兴学科。通过构建“药物-靶点-疾病”网络，将依据中医理论和经验为主的中药“翻译”成现代药理学理论，为传统中药与现代药理学间搭建了桥梁；通过预测揭示中药物质基础、作用靶点和分子机制网络，助力传统中药的现代化发展。基于此，对中药网络药理学的发展现状、研究模式与应用、面临的挑战及发展方向进行总结，为中药网络药理学阐释中医药科学内涵提供参考。

Traditional Chinese medicine (TCM) network pharmacology is an emerging discipline that reveals the relationship between TCM and the human body at a systemic level. By constructing a “drug-target-disease” network, TCM network pharmacology “translates” TCM, which is primarily based on TCM theory and experience, into modern pharmacological theory, building a bridge between TCM and modern pharmacology; The material basis, potential targets, and molecular mechanism networks of TCM are revealed through prediction, it greatly promotes the modernization of TCM. Based on this, this paper discusses the current development, research models and applications, challenges, and future directions of TCM network pharmacology, providing a reference for interpreting the scientific connotation of TCM.

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广西自然科学基金资助项目（2023GXNSFDA026047）；广西自然科学基金资助项目（2024GXNSFBA010088）；国家自然科学基金资助项目（82074347）；中央引导地方科技发展资金专项（防科ZY20221502）