便秘是临床上常见的、多发病性消化系统疾病，严重影响患者的生活质量。目前化学药虽然在短期内能够取得显著的成效，但长期使用却往往存在疗效逐渐减弱的问题，可能与人体对化学药的耐受性逐渐增强，及对人体的不良反应逐渐显现有关。相比之下，芦荟Aloe作为一种历史悠久的天然药物，在治疗便秘方面具有悠久的历史和广泛的应用。研究表明，芦荟具有治疗胃溃疡、泻下通便、调节肠道菌群组成和改善肠黏膜屏障功能等作用，可以有效治疗便秘。通过对芦荟治疗便秘的研究进展进行综述，旨在更全面地展示芦荟在治疗便秘方面的潜在应用价值，为今后芦荟的深入研究应用与治疗便秘相关药物的研发提供一定的参考价值。

Constipation is a common and prevalent disorder of the digestive system that severely impacts patients' quality of life. While chemical drugs can achieve significant short-term results, their long-term use often leads to diminishing efficacy, potentially due to increased tolerance and adverse reactions in the human body. In contrast, Luhui (Aloe), a natural remedy with a long history, has been widely used in the treatment of constipation. Research indicates that Aloe can treat gastric ulcers, promote bowel movements, regulate the composition of gut microbiota, and improve intestinal barrier function, effectively alleviating constipation. This review aims to comprehensively present the potential applications of Aloe in the treatment of constipation. By summarizing the advancements in research on Aloe for constipation, this article intends to provide valuable insights for further in-depth studies and the development of constipation-related medications utilizing Aloe.

福建医科大学高层次人才科研启动经费（60000166）