[关键词]
[摘要]
脂质代谢作为机体重要且复杂的生命过程,对生命活动具有重要意义。脂代谢的紊乱可直接引发酮症、脂肪肝、肥胖等代谢性疾病。中药因多靶点、多途径、不良反应相对较少等优点被广泛应用于脂代谢方面的研究,且中药在治疗肥胖等与脂质代谢紊乱相关的疾病方面历史悠久、临床疗效确切。通过对近年来中药有效成分在调节脂肪组织结构和功能方面的研究进行整理归纳,为中药药理学研究及中药的新药开发、老药新用提供新思路。
[Key word]
[Abstract]
As an important and complex process, lipid metabolism is of vital importance to life activities. Disorders of lipid metabolism might cause metabolic diseases such as ketosis, fatty liver and obesity. Traditional Chinese medicine (TCM) has been widely used in the study of lipid metabolism due to its advantages of multi-targets, multi-pathways and relatively low adverse reactions. Furthermore, it has a long history in treatments of diseases related to lipid metabolism disorders, and its clinical efficacy is reliable. According to the structural classification of active components of TCM, this review summarizes the recent researches of TCM on regulating the structure and function of adipose tissues, so as to provide new ideas for the subsequent new medicine development and repurposing.
[中图分类号]
R285
[基金项目]