目的 明确甘草研究现状，把握研究热点和前沿动态，为经济新常态下的甘草科研创新及甘草产业发展提供科学参考和理论依据。方法 在国内外核心学术期刊数据平台检索2000年1月1日—2021年12月31日有关甘草的文献，运用Coocation（COOC）软件进行数据处理和筛选，采用VOSviewer可视化技术从国家、机构、作者、关键词及期刊等方面对甘草的研究热点、前沿动态及研究主题的时序与地域分布进行梳理和总结。结果 2000—2021年，甘草相关研究发文量总体呈多元增长趋势。中国是甘草研究的核心国家，国内医药院校是甘草科研的主体机构。国际科研环境中对甘草的定位主要是“天然药物甘草”，研究主题集中于甘草的有效成分、药理活性、作用机制和生长特性；国内则多以“中药甘草”为研究对象，在甘草及复方的临床疗效及用药经验总结方面积累了大量科研成果。结论 甘草研究已进入多元、深入的稳定发展阶段，未来的研究主要是对现有研究成果的补充和拓展；用药经验的数据挖掘与传统用药规律分析是现阶段甘草的热门研究主题。

Objective To clarify the current situation of Gancao (Glycyrrhizae Radix et Rhizoma) research, to grasp the research hotspots and frontier dynamics, and to provide scientific reference and theoretical basis for the scientific research and innovation of Glycyrrhizae Radix et Rhizoma and the development of the Glycyrrhizae Radix et Rhizoma industry under the new economic normal. Methods Literature on Glycyrrhizae Radix et Rhizoma was searched from January 1, 2000 to December 31, 2021 on the data platform of core academic journals in and out of China, Coocation (COOC) software was used for data processing and screening, and VOSviewer visualization technology was used to sort out and summarize the research hotspots, frontier dynamics, and temporal and geographic distributions of the research topics of Glycyrrhizae Radix et Rhizoma in terms of countries, institutions, authors, keywords, and journals. Results Between 2000 and 2021, the overall trend of Glycyrrhizae Radix et Rhizoma research publications showed a multifaceted growth. China is the core country of Glycyrrhizae Radix et Rhizoma research, and domestic medical colleges and universities are the main institutions of Glycyrrhizae Radix et Rhizoma research. In the international scientific research environment, Glycyrrhizae Radix et Rhizoma is mainly positioned as “natural medicine Glycyrrhizae Radix et Rhizoma”, and the research theme focuses on the active ingredients, pharmacological activity, mechanism of action, and growth characteristics of Glycyrrhizae Radix et Rhizoma; In China, most of the research focuses on “Chinese medicine Glycyrrhizae Radix et Rhizoma”, and a large number of scientific research results have been accumulated in terms of clinical efficacy of Glycyrrhizae Radix et Rhizoma and compound prescription and summarization of medication experience. Conclusion Licorice research has entered a diversified, in-depth, and stable development stage, and future research will mainly complement and expand the existing research results. Data mining of medication experience and analysis of traditional medication patterns are popular research topics in Glycyrrhizae Radix et Rhizoma at this stage.

中国工程院战略研究与咨询项目（GS2021ZDA06）；道地药材生态种植及质量保障项目（国中医药科技[2020]153号）；财政部和农业农村部：国家现代农业产业技术体系项目（CARS-21）；甘肃省珍稀中药资源评价与保护利用工程研究中心开放基金项目（GSZXZY202203）；中医药产业创新联合体项目“道地陇药产业化核心技术攻关及质量提升”（23ZDFA013-1）