[关键词]
[摘要]
目的 探寻植物类药材农残检测研究的热点与发展趋势。方法 通过对中国知网(CNKI)和Web of Science核心数据库(WoSCC)自建库以来有关该主题的文献进行检索,根据所得数据绘制发文量趋势图,并对纳入的文献分别使用VOSviewer软件进行关键词、作者共现分析,使用CiteSpace 6.1.R6 Advanced软件进行机构共现、关键突现与聚类分析、时间线分布图绘制。结果 筛选出521篇中文文献和153篇英文文献,发现该领域在2005年之后迅猛发展。国内领衔的作者与机构为以薛健为代表的中国医学科学院、国外为以Tagami Takaomi为代表的日本大阪府立公共研究所。研究主要集中在检测基质(金银花、人参、三七、黄芪等)、农残类型(有机氯、有机磷及拟除虫菊酯类)和检测技术(质谱联用技术等)等方面,且整体趋势向植物类药材中多种农药的同时检测,技术手段更趋高效、简单化。结论 该领域的发展受益于学科交融及《中国药典》对药材农残限量标准和检测方法的不断完善,未来发展趋势将聚焦于质量标准研究和风险评估。
[Key word]
[Abstract]
Objective To obtain the hotspots and development trends of pesticide residue detection research on botanical medicinal materials. Methods The literatures on this topic since the establishment of China Knowledge Network (CNKI) and Web of Science Core (WoSCC) databases were searched, based on the obtained data, the trend of postings were plotted and the keyword and author co-occurrence were analyzed by VOSviewer software and the institutional co-occurrence, key emergence and clustering analysis, and timeline distribution mapping for the included literatures were conducted by CiteSpace 6.1.R6 Advanced software, respectively. Results A total of 521 Chinese literatures and 153 English literatures were conducted, and it was found that the field developed rapidly after 2005. The leading authors and institutions in China are the Chinese Academy of Medical Sciences represented by XUE Jian, and abroad are the Osaka Prefectural Public Research Institute represented by Tagami Takaomi. The research mainly focuses on the detection matrix [Jinyinhua (Lonicerae Japonicae Flos), Renshen (Ginseng Radix et Rhizoma), Sanqi (Notoginseng Radix et Rhizoma), Huangqi (Astragali Radix)], types of pesticide residues (organochlorine, organophosphorus and pyrethroids) and detection techniques (mass spectrometry coupling techniques), and the overall trend is toward the simultaneous detection of multiple pesticides in different medicinal parts of herbs, with more efficient and simpler technical means. Conclusion The development of this field benefits from the convergence of disciplines and the continuous improvement of the Chinese Pharmacopoeia in terms of pesticide residue limits and detection methods, and the future development trend will focus on quality standard research and risk assessment.
[中图分类号]
[基金项目]
国家自然科学基金项目(82174209)